PDB entry 6ckr

View 6ckr on RCSB PDB site
Description: Crystal Structure of BRD4 with QC4956
Class: gene regulation/inhibitor
Keywords: BRD4, Acetyllysine, epigenetics, GENE REGULATION-INHIBITOR complex
Deposited on 2018-02-28, released 2018-05-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-05-02, with a file datestamp of 2018-04-27.
Experiment type: XRAY
Resolution: 1.62 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60885 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.07: d6ckra1, d6ckra2
  • Chain 'B':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6ckrb_
  • Heterogens: F5V, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6ckrA (A:)
    mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
    tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
    elptee
    

    Sequence, based on observed residues (ATOM records): (download)
    >6ckrA (A:)
    mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
    tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
    elpte
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6ckrB (B:)
    mnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiik
    tpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkin
    elptee
    

    Sequence, based on observed residues (ATOM records): (download)
    >6ckrB (B:)
    nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
    pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
    lptee