PDB entry 6cit

View 6cit on RCSB PDB site
Description: Crystal Structure of MVM NS2 NES Peptide in complex with CRM1-Ran-RanBP1
Class: protein transport
Keywords: Karyopherin, CRM1, XPO1, Exportin-1, MVM, NES, Nuclear Export, PROTEIN TRANSPORT
Deposited on 2018-02-25, released 2018-06-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-06-27, with a file datestamp of 2018-06-22.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP-binding nuclear protein ran
    Species: Homo sapiens [TaxId:9606]
    Gene: RAN, ARA24, OK/SW-cl.81
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6cita_
  • Chain 'B':
    Compound: Ran-specific GTPase-activating protein 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: YRB1, CST20, HTN1, SFO1, YDR002W, YD8119.08
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6citb_
  • Chain 'C':
    Compound: Exportin-1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: CRM1, KAP124, XPO1, YGR218W, G8514
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30822 (3-378)
      • expression tag (1-2)
    • Uniprot P30822 (379-End)
      • conflict (502)
      • conflict (504-506)
      • conflict (987)
  • Chain 'D':
    Compound: ns2
    Species: Minute virus of mice [TaxId:10794]
    Gene: NS2
    Database cross-references and differences (RAF-indexed):
    • PDB 6CIT (Start-20)
  • Heterogens: GNP, MG, GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6citA (A:)
metgsshhhhhhssglprgshmaaqgepqvqfklvlvgdggtgkttfvkrhltgefekky
vatlgvevhplvfhtnrgpikfnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyk
nvpnwhrdlvrvcenipivlcgnkvdikdrkvkaksivfhrkknlqyydisaksnynfek
pflwlarkligdpnlefvampalappevvmdpalaaqyehdlevaqttalpdedddl

    Sequence, based on observed residues (ATOM records): (download) 
    >6citA (A:)
vqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdtag
qekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdikd
rkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvampalappevd
palaaqyehdlevaqttalpdedddl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6citB (B:)
ggsdihfepvvhlekvdvktmeedeevlykvraklfrfdadakewkergtgdckflknkk
tnkvrilmrrdktlkicanhiiapeytlkpnvgsdrswvyactadiaegeaeaftfairf
gskenadkfkeefekaqeinkka

    Sequence, based on observed residues (ATOM records): (download) 
    >6citB (B:)
ihfepvvtmeedeevlykvraklfrfdadakewkergtgdckflknkktnkvrilmrrdk
tlkicanhiiapeytlkpnvgsdrswvyactadiaegeaeaftfairfgskenadkfkee
fekaqeinkka

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.