PDB entry 6cit
View 6cit on RCSB PDB site
Description: Crystal Structure of MVM NS2 NES Peptide in complex with CRM1-Ran-RanBP1
Class: protein transport
Keywords: Karyopherin, CRM1, XPO1, Exportin-1, MVM, NES, Nuclear Export, PROTEIN TRANSPORT
Deposited on
2018-02-25, released
2018-06-27
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-11-20, with a file datestamp of
2019-11-15.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: GTP-binding nuclear protein ran
Species: Homo sapiens [TaxId:9606]
Gene: RAN, ARA24, OK/SW-cl.81
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6cita_ - Chain 'B':
Compound: Ran-specific GTPase-activating protein 1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: YRB1, CST20, HTN1, SFO1, YDR002W, YD8119.08
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6citb_ - Chain 'C':
Compound: Exportin-1
Species: Saccharomyces cerevisiae [TaxId:4932]
Gene: CRM1, KAP124, XPO1, YGR218W, G8514
Database cross-references and differences (RAF-indexed):
- Uniprot P30822 (3-378)
- Uniprot P30822 (379-End)
- conflict (502)
- conflict (504-506)
- conflict (987)
- Chain 'D':
Compound: ns2
Species: Minute virus of mice [TaxId:10794]
Gene: NS2
Database cross-references and differences (RAF-indexed):
- Heterogens: GNP, MG, GOL, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6citA (A:)
metgsshhhhhhssglprgshmaaqgepqvqfklvlvgdggtgkttfvkrhltgefekky
vatlgvevhplvfhtnrgpikfnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyk
nvpnwhrdlvrvcenipivlcgnkvdikdrkvkaksivfhrkknlqyydisaksnynfek
pflwlarkligdpnlefvampalappevvmdpalaaqyehdlevaqttalpdedddl
Sequence, based on observed residues (ATOM records): (download)
>6citA (A:)
vqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdtag
qekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdikd
rkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlefvampalappevd
palaaqyehdlevaqttalpdedddl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6citB (B:)
ggsdihfepvvhlekvdvktmeedeevlykvraklfrfdadakewkergtgdckflknkk
tnkvrilmrrdktlkicanhiiapeytlkpnvgsdrswvyactadiaegeaeaftfairf
gskenadkfkeefekaqeinkka
Sequence, based on observed residues (ATOM records): (download)
>6citB (B:)
ihfepvvtmeedeevlykvraklfrfdadakewkergtgdckflknkktnkvrilmrrdk
tlkicanhiiapeytlkpnvgsdrswvyactadiaegeaeaftfairfgskenadkfkee
fekaqeinkka
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.