PDB entry 6c86

View 6c86 on RCSB PDB site
Description: Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine
Class: ligase
Keywords: SSGCID, Lysine--tRNA ligase, Cryptosporidium parvum, ATP binding, aminoacylation, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, LIGASE
Deposited on 2018-01-24, released 2018-02-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lysine--tRNA ligase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd4_2370
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5CR27 (21-End)
      • expression tag (20)
    Domains in SCOPe 2.08: d6c86a1, d6c86a2, d6c86a3
  • Chain 'B':
    Compound: Lysine--tRNA ligase
    Species: Cryptosporidium parvum (strain Iowa II) [TaxId:353152]
    Gene: cgd4_2370
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5CR27 (21-End)
      • expression tag (20)
    Domains in SCOPe 2.08: d6c86b1, d6c86b2, d6c86b3
  • Heterogens: KAA, EDO, NA, SO4, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6c86A (A:)
    mahhhhhhmgtleaqtqgpgshytdnrykmmecikdagrpfyphkfkismslpayalkyg
    nvengyidkdttlslsgrvtsirssssklifydifceeqkvqiianimehdistgefsvs
    hseirrgdvvgftgfpgkskrgelslfsksvvllspcyhmlptaisglkdqevryrqryl
    dlmlneesrkvfklrsraikyirnyfdrlgflevetpmlnmiyggaaarpfityhnelet
    qlymriapelylkqlivggldkvyeigknfrnegidlthnpeftamefymayadyydlmd
    lteelisglvleihgslkipyhpdgpegkcieidfttpwkrfsfveeiesglgeklkrpl
    dsqenidfmvemcekheielphprtaaklldklaghfvetkctnpsfiidhpqtmsplak
    whrekpemterfelfvlgkelcnaytelneplqqrkffeqqadakasgdveacpidetfc
    lalehglpptggwglgidrlimfladknnikevilfpamrnvkqnaqhsnqhsgn
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c86A (A:)
    shytdnrykmmecikdagrpfyphkfkismslpayalkygnvengyidkdttlslsgrvt
    sirssssklifydifceeqkvqiianimehdistgefsvshseirrgdvvgftgfpgksk
    rgelslfsksvvllspcyhmlptaisglkdqevryrqryldlmlneesrkvfklrsraik
    yirnyfdrlgflevetpmlnmiyggaaarpfityhneletqlymriapelylkqlivggl
    dkvyeigknfrnegidlthnpeftamefymayadyydlmdlteelisglvleihgslkip
    yhpdgpegkcieidfttpwkrfsfveeiesglgeklkrpldsqenidfmvemcekheiel
    phprtaaklldklaghfvetkctnpsfiidhpqtmsplakwhrekpemterfelfvlgke
    lcnaytelneplqqrkffeqqadakasgdveacpidetfclalehglpptggwglgidrl
    imfladknnikevilfpamrn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6c86B (B:)
    mahhhhhhmgtleaqtqgpgshytdnrykmmecikdagrpfyphkfkismslpayalkyg
    nvengyidkdttlslsgrvtsirssssklifydifceeqkvqiianimehdistgefsvs
    hseirrgdvvgftgfpgkskrgelslfsksvvllspcyhmlptaisglkdqevryrqryl
    dlmlneesrkvfklrsraikyirnyfdrlgflevetpmlnmiyggaaarpfityhnelet
    qlymriapelylkqlivggldkvyeigknfrnegidlthnpeftamefymayadyydlmd
    lteelisglvleihgslkipyhpdgpegkcieidfttpwkrfsfveeiesglgeklkrpl
    dsqenidfmvemcekheielphprtaaklldklaghfvetkctnpsfiidhpqtmsplak
    whrekpemterfelfvlgkelcnaytelneplqqrkffeqqadakasgdveacpidetfc
    lalehglpptggwglgidrlimfladknnikevilfpamrnvkqnaqhsnqhsgn
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c86B (B:)
    shytdnrykmmecikdagrpfyphkfkismslpayalkygnvengyidkdttlslsgrvt
    sirssssklifydifceeqkvqiianimehdistgefsvshseirrgdvvgftgfpgksk
    rgelslfsksvvllspcyhmlptaidqevryrqryldlmlneesrkvfklrsraikyirn
    yfdrlgflevetpmlnmiyggaaarpfityhneletqlymriapelylkqlivggldkvy
    eigknfrnegidlthnpeftamefymayadyydlmdlteelisglvleihgslkipyhpd
    gpegkcieidfttpwkrfsfveeiesglgeklkrpldsqenidfmvemcekheielphpr
    taaklldklaghfvetkctnpsfiidhpqtmsplakwhrekpemterfelfvlgkelcna
    ytelneplqqrkffeqqadakasgdveacpidetfclalehglpptggwglgidrlimfl
    adknnikevilfpamrn