PDB entry 6c7p

View 6c7p on RCSB PDB site
Description: Crystal structure of D477G ACO/RPE65 chimera, monoclinic crystal form
Class: oxidoreductase
Keywords: non-heme iron, chimera, 7-bladed propeller, dominant mutation, OXIDOREDUCTASE
Deposited on 2018-01-23, released 2018-04-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-04-25, with a file datestamp of 2018-04-20.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Apocarotenoid-15,15'-oxygenase
    Species: Synechocystis sp. (strain PCC 6803 / Kazusa) [TaxId:1111708]
    Gene: sll1541
    Database cross-references and differences (RAF-indexed):
    • Uniprot P74334 (Start-489)
      • engineered mutation (43-44)
      • engineered mutation (430-431)
      • engineered mutation (434-436)
      • engineered mutation (441)
      • engineered mutation (460)
      • engineered mutation (462)
    Domains in SCOPe 2.07: d6c7pa_
  • Chain 'B':
    Compound: Apocarotenoid-15,15'-oxygenase
    Species: Synechocystis sp. (strain PCC 6803 / Kazusa) [TaxId:1111708]
    Gene: sll1541
    Database cross-references and differences (RAF-indexed):
    • Uniprot P74334 (Start-489)
      • engineered mutation (43-44)
      • engineered mutation (430-431)
      • engineered mutation (434-436)
      • engineered mutation (441)
      • engineered mutation (460)
      • engineered mutation (462)
    Domains in SCOPe 2.07: d6c7pb_
  • Heterogens: FE2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6c7pA (A:)
    mvtspptsspsqrsyspqdwlrgyqsqpqewdywvedvegsiplwlqgtlyrngpgllei
    gdrplkhpfdgdgmvtafkfpgdgrvhfqskfvrtqgyveeqkagkmiyrgvfgsqpagg
    wlktifdlrlkniantnitywgdrllalweggqphrlepsnlatiglddlggilaegqpl
    sahpridpastfdggqpcyvtfsiksslsstltlleldpqgkllrqktetfpgfafihdf
    aitphyaiflqnnvtlnglpylfglrgagecvqfhpdkpaqiilvprdggeikripvqag
    fvfhhanafeengkiildsicynslpqvdtdgdfrstnfdnldpgqlwrftidpaaatve
    kqlmvsrccefpvvhpqqvgrpyryvymgaahhstgnaplqailkvdlesgtetlrsfap
    hgfagepifvshpgaleeddgvllcliykadlhrselvilnakditapaiatlklkhhip
    yplhgswaqt
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c7pA (A:)
    sqrsyspqdwlrgyqsqpqewdywvedvegsiplwlqgtlyrngpglleigdrplkhpfd
    gdgmvtafkfpgdgrvhfqskfvrtqgyveeqkagkmiyrgvfgsqpaggwlktifdlrl
    kniantnitywgdrllalweggqphrlepsnlatiglddlggilaegqplsahpridpas
    tfdggqpcyvtfsikslsstltlleldpqgkllrqktetfpgfafihdfaitphyaiflq
    nnvtlnglpylfglrgagecvqfhpdkpaqiilvprdggeikripvqagfvfhhanafee
    ngkiildsicynslpqvddfrstnfdnldpgqlwrftidpaaatvekqlmvsrccefpvv
    hpqqvgrpyryvymgaahhstgnaplqailkvdlesgtetlrsfaphgfagepifvshpg
    aleeddgvllcliykadlhrselvilnakditapaiatlklkhhipyplhgswaqt
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6c7pB (B:)
    mvtspptsspsqrsyspqdwlrgyqsqpqewdywvedvegsiplwlqgtlyrngpgllei
    gdrplkhpfdgdgmvtafkfpgdgrvhfqskfvrtqgyveeqkagkmiyrgvfgsqpagg
    wlktifdlrlkniantnitywgdrllalweggqphrlepsnlatiglddlggilaegqpl
    sahpridpastfdggqpcyvtfsiksslsstltlleldpqgkllrqktetfpgfafihdf
    aitphyaiflqnnvtlnglpylfglrgagecvqfhpdkpaqiilvprdggeikripvqag
    fvfhhanafeengkiildsicynslpqvdtdgdfrstnfdnldpgqlwrftidpaaatve
    kqlmvsrccefpvvhpqqvgrpyryvymgaahhstgnaplqailkvdlesgtetlrsfap
    hgfagepifvshpgaleeddgvllcliykadlhrselvilnakditapaiatlklkhhip
    yplhgswaqt
    

    Sequence, based on observed residues (ATOM records): (download)
    >6c7pB (B:)
    sqrsyspqdwlrgyqsqpqewdywvedvegsiplwlqgtlyrngpglleigdrplkhpfd
    gdgmvtafkfpgdgrvhfqskfvrtqgyveeqkagkmiyrgvfgsqpwlktifdlrlkni
    antnitywgdrllalweggqphrlepsnlatiglddlggilaegqplsahpridpastfd
    ggqpcyvtfsiksslsstltlleldpqgkllrqktetfpgfafihdfaitphyaiflqnn
    vtlnglpylfglrgagecvqfhpdkpaqiilvprdggeikripvqagfvfhhanafeeng
    kiildsicynslpqvddfrstnfdnldpgqlwrftidpaaatvekqlmvsrccefpvvhp
    qqvgrpyryvymgaahhstgnaplqailkvdlesgtetlrsfaphgfagepifvshpgal
    eeddgvllcliykadlhrselvilnakditapaiatlklkhhipyplhgswaqt