PDB entry 6c5f

View 6c5f on RCSB PDB site
Description: Human D-Dopachrome tautomerase (D-DT)/ macrophage migration inhibitory factor 2 (MIF2) complexed with the selective inhibitor 4-CPPC
Class: cytokine
Keywords: selective inhibitor, CYTOKINE
Deposited on 2018-01-16, released 2018-06-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-07-11, with a file datestamp of 2018-07-06.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: D-dopachrome decarboxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: Ddt
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6c5fa_
  • Chain 'B':
    Compound: D-dopachrome decarboxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: Ddt
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6c5fb_
  • Chain 'C':
    Compound: D-dopachrome decarboxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: Ddt
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6c5fc_
  • Heterogens: 7L9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6c5fA (A:)
pfleldtnlpanrvpaglekrlcaaaasilgkpadrvnvtvrpglamalsgstepcaqls
issigvvgtaednrshsahffefltkelalgqdrilirffpleswqigkigtvmtfl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6c5fB (B:)
pfleldtnlpanrvpaglekrlcaaaasilgkpadrvnvtvrpglamalsgstepcaqls
issigvvgtaednrshsahffefltkelalgqdrilirffpleswqigkigtvmtfl

    Sequence, based on observed residues (ATOM records): (download) 
    >6c5fB (B:)
pfleldtnlpanrvpaglekrlcaaaasilgkpadrvnvtvrpglamalsgstepcaqls
issigvvgtaednrshsahffefltkelalgqdrilirffpleswqigkigtv

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6c5fC (C:)
pfleldtnlpanrvpaglekrlcaaaasilgkpadrvnvtvrpglamalsgstepcaqls
issigvvgtaednrshsahffefltkelalgqdrilirffpleswqigkigtvmtfl