PDB entry 6bu1

View 6bu1 on RCSB PDB site
Description: Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-Br-3-OH-phenyldiketoacid
Class: STRUCTURAL GENOMICS,Transferase
Keywords: Acetyltransferase, Structural Genomics, TB Structural Genomics Consortium, TBSGC, TRANSFERASE, TRANSFERASE-TRANSFERASE inhibitor complex
Deposited on 2017-12-08, released 2018-09-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: malate synthase g
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A5U3K4
      • engineered mutation (618)
    Domains in SCOPe 2.08: d6bu1a_
  • Heterogens: E9S, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6bu1A (A:)
mtdrvsvgnlriarvlydfvnnealpgtdidpdsfwagvdkvvadltpqnqallnardel
qaqidkwhrrrviepidmdayrqflteigyllpepddftittsgvdaeitttagpqlvvp
vlnarfalnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkflddsv
plssgsfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhglhie
ilidpesqvgttdragvkdvilesaittimdfedsvaavdaadkvlgyrnwlglnkgdla
aavdkdgtaflrvlnrdrnytapgggqftlpgrslmfvrnvghlmtndaivdtdgsevfe
gimdalftgliaihglkasdvngplinsrtgsiyivkpkmhgpaevaftcelfsrvedvl
glpqntmkigimdeerrttvnlkacikaaadrvvfintgfldrtgdeihtsmeagpmvrk
gtmksqpwilayedhnvdaglaagfsgraqvgkgmwtmtelmadmvetkiaqpragasta
wvpsptaatlhalhyhqvdvaavqqglagkrratieqlltiplakelawapdeireevdn
ncqsilgyvvrwvdqgvgaskvpdihdvalmedratlrissqllanwlrhgvitsadvra
slermaplvdrqnagdvayrpmapnfddsiaflaaqelilsgaqqpngytepilhrrrre
fkaraaekpapsdragddaar

    Sequence, based on observed residues (ATOM records): (download) 
    >6bu1A (A:)
drvsvgnlriarvlydfvnnealpgtdidpdsfwagvdkvvadltpqnqallnardelqa
qidkwhrrrviepidmdayrqflteigyllpepddftittsgvdaeitttagpqlvvpvl
narfalnaanarwgslydalygtdvipetdgaekgptynkvrgdkviayarkflddsvpl
ssgsfgdatgftvqdgqlvvalpdkstglanpgqfagytgaaesptsvllinhglhieil
idpesqvgttdragvkdvilesaittimdfedsvaavdaadkvlgyrnwlglnkgdlaar
vlnrdrnytapgggqftlpgrslmfvrnvghlmtndaivdtdgsevfegimdalftglia
ihglkasgplinsrtgsiyivkpkmhgpaevaftcelfsrvedvlglpqntmkigimdee
rrttvnlkacikaaadrvvfintgfldrtgdeihtsmeagpmvrkgtmksqpwilayedh
nvdaglaagfsgraqvgkgmwtmtelmadmvetkiaqpragastawvpsptaatlhalhy
hqvdvaavqqglagkrratieqlltiplakelawapdeireevdnncqsilgyvvrwvdq
gvgaskvpdihdvalmedratlrissqllanwlrhgvitsadvraslermaplvdrqnag
dvayrpmapnfddsiaflaaqelilsgaqqpngytepilhrrrrefkaraae