PDB entry 6btz

View 6btz on RCSB PDB site
Description: Crystal structure of the PI3KC2alpha C2 domain in space group C121
Class: transferase
Keywords: C2 domain, lipid binding, phosphoinositide, PI3-kinase, Transferase
Deposited on 2017-12-08, released 2018-10-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-12-19, with a file datestamp of 2018-12-14.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PIK3C2A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6btza_
  • Chain 'B':
    Compound: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PIK3C2A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6btzb_
  • Chain 'C':
    Compound: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PIK3C2A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6btzc_
  • Chain 'D':
    Compound: Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: PIK3C2A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6btzd_
  • Heterogens: SO4, O4B, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6btzA (A:)
snaiggavklsisyrngtlfimvmhikdlvtedgadpnpyvktyllpdnhktskrktkis
rktrnptfnemlvysgysketlrqrelqlsvlsaeslrenfflggvtlplkdfnlsketv
kwyqltaatyl

    Sequence, based on observed residues (ATOM records): (download) 
    >6btzA (A:)
iggavklsisyrngtlfimvmhikdlvtedgadpnpyvktyllpdnhktskrktkisrkt
rnptfnemlvysgysketlrqrelqlsvlsaeslrenfflggvtlplkdfnlsketvkwy
qltaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6btzB (B:)
snaiggavklsisyrngtlfimvmhikdlvtedgadpnpyvktyllpdnhktskrktkis
rktrnptfnemlvysgysketlrqrelqlsvlsaeslrenfflggvtlplkdfnlsketv
kwyqltaatyl

    Sequence, based on observed residues (ATOM records): (download) 
    >6btzB (B:)
iggavklsisyrngtlfimvmhikdlvtedgadpnpyvktyllpdnhktskrktkisrkt
rnptfnemlvysgysketlrqrelqlsvlsaeslrenfflggvtlplkdfnlsketvkwy
qltaa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6btzC (C:)
snaiggavklsisyrngtlfimvmhikdlvtedgadpnpyvktyllpdnhktskrktkis
rktrnptfnemlvysgysketlrqrelqlsvlsaeslrenfflggvtlplkdfnlsketv
kwyqltaatyl

    Sequence, based on observed residues (ATOM records): (download) 
    >6btzC (C:)
iggavklsisyrngtlfimvmhikdlvtedgadpnpyvktyllpdnhktskrktkisrkt
rnptfnemlvysgysketlrqrelqlsvlsaeslrenfflggvtlplkdfnlsketvkwy
qltaat

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6btzD (D:)
snaiggavklsisyrngtlfimvmhikdlvtedgadpnpyvktyllpdnhktskrktkis
rktrnptfnemlvysgysketlrqrelqlsvlsaeslrenfflggvtlplkdfnlsketv
kwyqltaatyl

    Sequence, based on observed residues (ATOM records): (download) 
    >6btzD (D:)
iggavklsisyrngtlfimvmhikdlvtedgadpnpyvktyllpdnhktskrktkisrkt
rnptfnemlvysgysketlrqrelqlsvlsaeslrenfflggvtlplkdfnlsketvkwy
qltaat