PDB entry 6bt5

View 6bt5 on RCSB PDB site
Description: Human mGlu8 Receptor complexed with L-AP4
Class: signaling protein
Keywords: mGluR8, GRM8, L-AP4, GENE ID: 2918, SIGNALING PROTEIN
Deposited on 2017-12-05, released 2018-02-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.92 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metabotropic glutamate receptor 8
    Species: Homo sapiens [TaxId:9606]
    Gene: GRM8, GPRC1H, MGLUR8
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00222 (0-477)
      • conflict (209)
      • expression tag (478)
    Domains in SCOPe 2.08: d6bt5a1, d6bt5a2
  • Chain 'B':
    Compound: Metabotropic glutamate receptor 8
    Species: Homo sapiens [TaxId:9606]
    Gene: GRM8, GPRC1H, MGLUR8
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00222 (0-End)
      • conflict (209)
    Domains in SCOPe 2.08: d6bt5b_
  • Heterogens: E7P, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6bt5A (A:)
ahsirvdgdiilgglfpvhakgergvpcgelkkekgihrleamlyaidqinkdpdllsni
tlgvrildtcsrdtyaleqsltfvqaliekdasdvkcangdppiftkpdkisgvigaaas
svsimvanilrlfkipqisyastapelsdntrydffsrvvppdsyqaqamvdivtalgwn
yvstlasegnygesgveaftqisreiggvsiaqsqkipreprpgefekiikrlletpnar
avimfaneddirrileaakklnqsghflwigsdswgskiapvyqqeeiaegavtilpkra
sidgfdryfrsrtlannrrnvwfaefweenfgcklgshgkrnshikkctgleriardssy
eqegkvqfvidavysmayalhnmhkdlcpgyiglcprmstidgkellgyiravnfngsag
tpvtfnengdapgrydifqyqitnksteykvighwtnqlhlkvedmqwahrehthpase

    Sequence, based on observed residues (ATOM records): (download) 
    >6bt5A (A:)
ahsirvdgdiilgglfpvhakgergvpcgelkkekgihrleamlyaidqinkdpdllsni
tlgvrildtcsrdtyaleqsltfvqkisgvigaaassvsimvanilrlfkipqisyasta
pelsdntrydffsrvvppdsyqaqamvdivtalgwnyvstlasegnygesgveaftqisr
eiggvsiaqsqkipreprpgefekiikrlletpnaravimfaneddirrileaakklnqs
ghflwigsdswgskiapvyqqeeiaegavtilpkrasidgfdryfrsrtlannrrnvwfa
efweenfgcklkctgleriardssyeqegkvqfvidavysmayalhnmhkdlcpgyiglc
prmstidgkellgyiravnfngsagtpvtfnengdapgrydifqyqitnksteykvighw
tnqlhlkvedmqwahrthpase

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6bt5B (B:)
ahsirvdgdiilgglfpvhakgergvpcgelkkekgihrleamlyaidqinkdpdllsni
tlgvrildtcsrdtyaleqsltfvqaliekdasdvkcangdppiftkpdkisgvigaaas
svsimvanilrlfkipqisyastapelsdntrydffsrvvppdsyqaqamvdivtalgwn
yvstlasegnygesgveaftqisreiggvsiaqsqkipreprpgefekiikrlletpnar
avimfaneddirrileaakklnqsghflwigsdswgskiapvyqqeeiaegavtilpkra
sidgfdryfrsrtlannrrnvwfaefweenfgcklgshgkrnshikkctgleriardssy
eqegkvqfvidavysmayalhnmhkdlcpgyiglcprmstidgkellgyiravnfngsag
tpvtfnengdapgrydifqyqitnksteykvighwtnqlhlkvedmqwahrehthpase

    Sequence, based on observed residues (ATOM records): (download) 
    >6bt5B (B:)
ahsirvdgdiilgglfpvhakgergvpcgelkkekgihrleamlyaidqinkdpdllsni
tlgvrildtcsrdtyaleqsltfvqkisgvigaaassvsimvanilrlfkipqisyasta
pelsdntrydffsrvvppdsyqaqamvdivtalgwnyvstlasegnygesgveaftqisr
eiggvsiaqsqkipreprpgefekiikrlletpnaravimfaneddirrileaakklnqs
ghflwigsdswgskiapvyqqeeiaegavtilpkrasidgfdryfrsrtlannrrnvwfa
efweenfgcklkctgleriardssyeqegkvqfvidavysmayalhnmhkdlcpgyiglc
prmstidgkellgyiravnfngsagtpvtfnengdapgrydifqyqitnksteykvighw
tnqlhlkvedmqw