PDB entry 6bq0

View 6bq0 on RCSB PDB site
Description: Structure of human monoacylglycerol lipase bound to a covalent inhibitor
Class: Hydrolase/Hydrolase Inhibitor
Keywords: Monoacylglycerol lipase, covalent inhibitor, SBDD, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2017-11-27, released 2018-03-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-04-25, with a file datestamp of 2018-04-20.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Monoglyceride lipase
    Species: Homo sapiens [TaxId:9606]
    Gene: MGLL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6bq0a_
  • Chain 'B':
    Compound: Monoglyceride lipase
    Species: Homo sapiens [TaxId:9606]
    Gene: MGLL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6bq0b_
  • Heterogens: E3A, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6bq0A (A:)
masrgshhhhhhgagdrgpefpssmpeessprrtpqsipyqdlphlvnadgqylfcrywk
ptgtpkalifvshgagehsgryeelarmlmgldllvfahdhvghgqsegermvvsdfhvf
vrdvlqhvdsmqkdypglpvfllghsmggaiailtaaerpghfagmvlisplvlanpesa
ttfkvlaakvlnlvlpnlslgpidssvlsrnktevdiynsdplicraglkvcfgiqllna
vsrveralpkltvpflllqgsadrlcdskgayllmelaksqdktlkiyegayhvlhkelp
evtnsvfheinmwvsqrtatagtaspplevdlqgdhglsawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6bq0A (A:)
dlphlvnadgqylfcrywkptgtpkalifvshgagehsgryeelarmlmgldllvfahdh
vghgqsegermvvsdfhvfvrdvlqhvdsmqkdypglpvfllghsmggaiailtaaerpg
hfagmvlisplvlanpesattfkvlaakvlnlvlpnlslgpidssvlsrnktevdiynsd
plicraglkvcfgiqllnavsrveralpkltvpflllqgsadrlcdskgayllmelaksq
dktlkiyegayhvlhkelpevtnsvfheinmwvsqrtata

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6bq0B (B:)
masrgshhhhhhgagdrgpefpssmpeessprrtpqsipyqdlphlvnadgqylfcrywk
ptgtpkalifvshgagehsgryeelarmlmgldllvfahdhvghgqsegermvvsdfhvf
vrdvlqhvdsmqkdypglpvfllghsmggaiailtaaerpghfagmvlisplvlanpesa
ttfkvlaakvlnlvlpnlslgpidssvlsrnktevdiynsdplicraglkvcfgiqllna
vsrveralpkltvpflllqgsadrlcdskgayllmelaksqdktlkiyegayhvlhkelp
evtnsvfheinmwvsqrtatagtaspplevdlqgdhglsawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >6bq0B (B:)
sprrtpqsipyqdlphlvnadgqylfcrywkptgtpkalifvshgagehsgryeelarml
mgldllvfahdhvghgqsegermvvsdfhvfvrdvlqhvdsmqkdypglpvfllghsmgg
aiailtaaerpghfagmvlisplvlakvlaakvlnlvlpnlslgpidssvlsrnktevdi
ynsdplicraglkvcfgiqllnavsrveralpkltvpflllqgsadrlcdskgayllmel
aksqdktlkiyegayhvlhkelpevtnsvfheinmwvsqrtat