PDB entry 6bin

View 6bin on RCSB PDB site
Description: HLA-DRB1 in complex with Type II collagen peptide
Class: immune system
Keywords: HLA, MHC, citrulline, Rheumatoid Arthritis, IMMUNE SYSTEM
Deposited on 2017-11-02, released 2018-01-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-03-14, with a file datestamp of 2018-03-09.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DRA, HLA-DRA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01903 (4-180)
      • expression tag (2-3)
    Domains in SCOPe 2.07: d6bina1, d6bina2, d6bina3
  • Chain 'B':
    Compound: HLA class II histocompatibility antigen, DRB1-4 beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DRB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6binb1, d6binb2
  • Chain 'C':
    Compound: Type II Collagen 1240Cit 1237-1249
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6BIN (0-12)
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6binA (A:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    dtsgddddk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6binA (A:)
    eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
    iavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwl
    rngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6binB (B:)
    gsgdtrprfleqvkhechffngtervrfldryfyhqeeyvrfdsdvgeyravtelgrpda
    eywnsqkdlleqkraavdtycrhnygvgesftvqrrvypevtvypaktqplqhhnllvcs
    vngfypgsievrwfrngqeektgvvstgliqngdwtfqtlvmletvprsgevytcqvehp
    sltspltvewratggddddk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6binB (B:)
    dtrprfleqvkhechffngtervrfldryfyhqeeyvrfdsdvgeyravtelgrpdaeyw
    nsqkdlleqkraavdtycrhnygvgesftvqrrvypevtvypaktqplqhhnllvcsvng
    fypgsievrwfrngqeektgvvstgliqngdwtfqtlvmletvprsgevytcqvehpslt
    spltvewra
    

  • Chain 'C':
    No sequence available.