PDB entry 6bca
View 6bca on RCSB PDB site
Description: A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog
Class: signaling protein
Keywords: Rho GTPase Guanine Nucleotide Exchange Factors RhoGEF Pleckstrin Homology PH domain, SIGNALING PROTEIN
Deposited on
2017-10-20, released
2017-12-13
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-01-01, with a file datestamp of
2019-12-27.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: A-kinase anchor protein 13
Species: Homo sapiens [TaxId:9606]
Gene: AKAP13, BRX, HT31, LBC
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: A-kinase anchor protein 13
Species: Homo sapiens [TaxId:9606]
Gene: AKAP13, BRX, HT31, LBC
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: transforming protein rhoa
Species: Homo sapiens [TaxId:9606]
Gene: RHOA, ARH12, ARHA, RHO12
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6bcac_ - Chain 'F':
Compound: transforming protein rhoa
Species: Homo sapiens [TaxId:9606]
Gene: RHOA, ARH12, ARHA, RHO12
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6bcaf_ - Heterogens: MG, GSP, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>6bcaC (C:)
gildmaairkklvivgdgacgktcllivfskdqfpevyvptvfenyvadievdgkqvela
lwdtagqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvg
nkkdlrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematr
aalqa
Sequence, based on observed residues (ATOM records): (download)
>6bcaC (C:)
airkklvivgdgacgktcllivfskdqfpevyvptvfenyvadievdgkqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalqa
- Chain 'F':
Sequence, based on SEQRES records: (download)
>6bcaF (F:)
gildmaairkklvivgdgacgktcllivfskdqfpevyvptvfenyvadievdgkqvela
lwdtagqedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvg
nkkdlrndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematr
aalqa
Sequence, based on observed residues (ATOM records): (download)
>6bcaF (F:)
airkklvivgdgacgktcllivfskdqfpevyvptvfenyvadievdgkqvelalwdtag
qedydrlrplsypdtdvilmcfsidspdslenipekwtpevkhfcpnvpiilvgnkkdlr
ndehtrrelakmkqepvkpeegrdmanrigafgymecsaktkdgvrevfematraalqa