PDB entry 6b1i

View 6b1i on RCSB PDB site
Description: Disrupted hydrogen bond network impairs ATPase activity in an Hsc70 cysteine mutant
Class: chaperone
Keywords: Hsp70 family member, chaperone, ATPase
Deposited on 2017-09-18, released 2018-01-17
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein family A (Hsp70) member 8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6b1ia1, d6b1ia2
  • Chain 'B':
    Compound: Heat shock protein family A (Hsp70) member 8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6b1ib1, d6b1ib2
  • Heterogens: ADP, MG, PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6b1iA (A:)
mgsshhhhhhssglvprgshmaspavgidlgttyscvgvfqhgkveiiandqgnrttpsy
vaftdterligdaaknqvamnptntvfdakrligrrfddavvqsdmkhwpfmvvndagrp
kvqveykgetksfypeevssmvltkmkeiaeaylgktvtnavvtvpayfndsqrqatkda
gtiaglnvlriineptaaaiaygldkkvgaernvlifdlgggtfdvsiltiedgifevks
tagdthlggedfdnrmvnhfiaefkrkhkkdisenkravrrlrtacerakrtlssstqas
ieidslyegidfytsitrarfeelnadlfrgtldpvekalrdakldksqihdivlvggst
ripkiqkllqdffngkelnksinpdeavaygaavqaails

    Sequence, based on observed residues (ATOM records): (download) 
    >6b1iA (A:)
pavgidlgttyscvgvfqhgkveiiandqgnrttpsyvaftdterligdaaknqvamnpt
ntvfdakrligrrfddavvqsdmkhwpfmvvndagrpkvqveykgetksfypeevssmvl
tkmkeiaeaylgktvtnavvtvpayfndsqrqatkdagtiaglnvlriineptaaaiayg
ldkkvgaernvlifdlgggtfdvsiltiedgifevkstagdthlggedfdnrmvnhfiae
fkrkhkkdisenkravrrlrtacerakrtlssstqasieidslyegidfytsitrarfee
lnadlfrgtldpvekalrdakldksqihdivlvggstripkiqkllqdffngkelnksin
pdeavaygaavqaails

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6b1iB (B:)
mgsshhhhhhssglvprgshmaspavgidlgttyscvgvfqhgkveiiandqgnrttpsy
vaftdterligdaaknqvamnptntvfdakrligrrfddavvqsdmkhwpfmvvndagrp
kvqveykgetksfypeevssmvltkmkeiaeaylgktvtnavvtvpayfndsqrqatkda
gtiaglnvlriineptaaaiaygldkkvgaernvlifdlgggtfdvsiltiedgifevks
tagdthlggedfdnrmvnhfiaefkrkhkkdisenkravrrlrtacerakrtlssstqas
ieidslyegidfytsitrarfeelnadlfrgtldpvekalrdakldksqihdivlvggst
ripkiqkllqdffngkelnksinpdeavaygaavqaails

    Sequence, based on observed residues (ATOM records): (download) 
    >6b1iB (B:)
pavgidlgttyscvgvfqhgkveiiandqgnrttpsyvaftdterligdaaknqvamnpt
ntvfdakrligrrfddavvqsdmkhwpfmvvndagrpkvqveykgetksfypeevssmvl
tkmkeiaeaylgktvtnavvtvpayfndsqrqatkdagtiaglnvlriineptaaaiayg
ldkkvgaernvlifdlgggtfdvsiltiedgifevkstagdthlggedfdnrmvnhfiae
fkrkhkkdisenkravrrlrtacerakrtlssstqasieidslyegidfytsitrarfee
lnadlfrgtldpvekalrdakldksqihdivlvggstripkiqkllqdffngkelnksin
pdeavaygaavqaails