PDB entry 6b0g

View 6b0g on RCSB PDB site
Description: Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245
Class: immune system
Keywords: Transmission blocking vaccine, malaria, antibody, EGF-like domain, IMMUNE SYSTEM
Deposited on 2017-09-14, released 2017-11-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-29, with a file datestamp of 2017-11-24.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: 1245 Antibody, Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6B0G (0-End)
    Domains in SCOPe 2.08: d6b0gc1, d6b0gc2
  • Chain 'D':
    Compound: 1245 Antibody, Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6B0G
    Domains in SCOPe 2.08: d6b0gd_
  • Chain 'E':
    Compound: 25 kDa ookinete surface antigen
    Species: Plasmodium falciparum [TaxId:5843]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13829
      • conflict (92)
      • conflict (145)
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6b0gC (C:)
dvvmtqsplslpvtlgqpasiscrssqslvysdgntylswfqqrpgqsprrliykvsnrd
sgvpdrfsgsgsgtdftlkisrveaedvgvyycmqdthwpptfgggtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6b0gC (C:)
dvvmtqsplslpvtlgqpasiscrssqslvysdgntylswfqqrpgqsprrliykvsnrd
sgvpdrfsgsgsgtdftlkisrveaedvgvyycmqdthwpptfgggtkveikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6b0gD (D:)
qvqlvqsggevkkpgasvkvsckasgytftsygiswvrqapgqglewmgwisayngnrky
aqkvqgrvsmtidthtstanmelrslrsddtavyycakdrgdgdyryyyygmdvwgqgtt
vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

    Sequence, based on observed residues (ATOM records): (download) 
    >6b0gD (D:)
vqlvqsggevkkpgasvkvsckasgytftsygiswvrqapgqglewmgwisayngnrkya
qkvqgrvsmtidthtstanmelrslrsddtavyycakdrgdgdyryyyygmdvwgqgttv
tvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpav
lqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks

  • Chain 'E':
    No sequence available.