PDB entry 6ayc

View 6ayc on RCSB PDB site
Description: Naegleria fowleri CYP51-itraconazole complex
Class: oxidoreductase
Keywords: CYP51, sterol 14alpha-demethylase, OXIDOREDUCTASE
Deposited on 2017-09-08, released 2017-11-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-15, with a file datestamp of 2020-01-10.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein CYP51
    Species: Naegleria fowleri [TaxId:5763]
    Gene: NF0102700
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ayca1, d6ayca2
  • Heterogens: HEM, 1YN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6aycA (A:)
makktsskgklpprvpnlipyvgsfvsfaknpvqfiidnskkygdvftatilgkemtfln
hpkildtffkatdnelslrdvyrfmrpvfgtgvvydadstermmeqvkfvssglttarfr
vfvdifedeiahkvkelgpegtvdvaelmadliiftasrcllgdevrqylseknlgklyh
diddgisplsffypslpapkrdkarkavgeifqelldkrreehkkhperlldeskmdvvd
hlltqkykdgqeltdvhrigiliaglfagqhtssitsswtlmnvisnkkvlekvrkeqee
imgsdkvldydkvmkmdyleacmkealrmypplimimrmarkpreceqyiipkgnilvvs
psvagrctdtytnpdvfdperlterkehekfkygavpfgagrhkcigenfallqvksiis
illryfdmeyigkipdpsytslvvgpspptrmryklrkqqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6aycA (A:)
klpprvpnlipyvgsfvsfaknpvqfiidnskkygdvftatilgkemtflnhpkildtff
katdnelslrdvyrfmrpvfgtgvvydadstermmeqvkfvssglttarfrvfvdifede
iahkvkelgpegtvdvaelmadliiftasrcllgdevrqylseknlgklyhdiddgispl
sffypslpapkrdkarkavgeifqelldkrreehkkhperlldeskmdvvdhlltqkykd
gqeltdvhrigiliaglfagqhtssitsswtlmnvisnkkvlekvrkeqeeimgsdkvld
ydkvmkmdyleacmkealrmypplimimrmarkpreceqyiipkgnilvvspsvagrctd
tytnpdvfdperlterkehekfkygavpfgagrhkcigenfallqvksiisillryfdme
yigkipdpsytslvvgpspptrmryklrk