PDB entry 6aua

View 6aua on RCSB PDB site
Description: crystal structure of bruton's tyrosine kinase in complex with inhibitor cgi2625
Class: Transferase/transferase Inhibitor
Keywords: BTK, Transferase-transferase Inhibitor complex
Deposited on 2017-08-31, released 2018-09-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-09-12, with a file datestamp of 2018-09-07.
No data on structure quality are available

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase BTK
    Species: Homo sapiens [TaxId:9606]
    Gene: BTK, AGMX1, ATK, BPK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q06187 (0-262)
      • conflict (150)
      • expression tag (263-264)
    Domains in SCOPe 2.07: d6auaa_
  • Heterogens: GOL, SO4, BXJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6auaA (A:)
    sweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnls
    heklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyle
    skqflhrdlaarnclvndqgvvkvsdfglsayvlddeytssvgskfpvrwsppevlmysk
    fssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimysc
    whekaderptfkillsnildvmdan