PDB entry 6aqs

View 6aqs on RCSB PDB site
Description: Crystal structure of Plasmodium falciparum purine nucleoside phosphorylase (V181D) mutant complexed with DADMe-ImmG and phosphate
Class: transferase
Keywords: Plasmodium falciparum, purine nucleoside phosphorylase (PNP), Phosphorylase, PNP mutant, DADMe-ImmG, TRANSFERASE
Deposited on 2017-08-21, released 2018-02-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-03-14, with a file datestamp of 2018-03-09.
Experiment type: XRAY
Resolution: 1.57 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: purine nucleoside phosphorylase
    Species: Plasmodium falciparum [TaxId:5833]
    Gene: PNP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8T9Z7 (Start-245)
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6aqsa_
  • Heterogens: PO4, IM5, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6aqsA (A:)
smdnllrhlkiskeqitpvvlvvgdpgrvdkikvvcdsyvdlaynreyksvechykgqkf
lcvshgvgsagcavcfeelcqngakviiragscgslqpdlikrgdicicnaavredrvsh
llihgdfpavgdfdvydtlnkcaqelnvpvfngisvssdmyypnkiipsrledyskanaa
vdemelatlmvigtlrkvktggilivdgcpfkwdegdfdnnlvphqlenmikialgacak
latkya

    Sequence, based on observed residues (ATOM records): (download) 
    >6aqsA (A:)
nllrhlkiskeqitpvvlvvgdpgrvdkikvvcdsyvdlaynreyksvechykgqkflcv
shgvgsagcavcfeelcqngakviiragscgslqpdlikrgdicicnaavredrvshlli
hgdfpavgdfdvydtlnkcaqelnvpvfngisvssdmyypnkiipsrledyskanaavde
melatlmvigtlrkvktggilivdgcvphqlenmikialgacaklatkya