PDB entry 6aml

View 6aml on RCSB PDB site
Description: Phosphotriesterase variant S8
Class: hydrolase
Keywords: phosphotriesterase, organophosphate hydrolase, epistasis, directed evolution, laboratory evolution, HYDROLASE
Deposited on 2017-08-09, released 2018-08-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-08-08, with a file datestamp of 2018-08-03.
Experiment type: XRAY
Resolution: 1.46 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphotriesterase
    Species: Brevundimonas diminuta [TaxId:293]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A060GYS1
      • conflict (58)
      • conflict (183)
      • conflict (200-201)
      • conflict (207)
      • conflict (221)
      • conflict (227)
      • conflict (260)
      • conflict (273)
      • conflict (287)
    Domains in SCOPe 2.07: d6amla_
  • Chain 'G':
    Compound: phosphotriesterase
    Species: Brevundimonas diminuta [TaxId:293]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A060GYS1
      • conflict (58)
      • conflict (183)
      • conflict (200-201)
      • conflict (207)
      • conflict (221)
      • conflict (227)
      • conflict (260)
      • conflict (273)
      • conflict (287)
    Domains in SCOPe 2.07: d6amlg_
  • Heterogens: ZN, CAC, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6amlA (A:)
    mgdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrrasa
    agvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsmrlrsveeltqfflr
    eiqygiedtgiragiikvattgkvtpfqelvlraaaraslatgvpvtthtaasqrggeqq
    aaileseglspsrvcighsdaaddlsyhtalaargyligldsiphsavglgdnasasahl
    girswqtrallikalidqgytkqilvsndwlfgissyvtnimdvmdsgnpdgmafiplrv
    ipflrekgipqetlagitvtnparflsptlras
    

    Sequence, based on observed residues (ATOM records): (download)
    >6amlA (A:)
    drintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrrasaag
    vrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsmrlrsveeltqfflrei
    qygiedtgiragiikvattgkvtpfqelvlraaaraslatgvpvtthtaasqrggeqqaa
    ileseglspsrvcighsdaaddlsyhtalaargyligldsiphsavswqtrallikalid
    qgytkqilvsndwlfgissyvtnimdvmdsgnpdgmafiplrvipflrekgipqetlagi
    tvtnparflsptlr
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >6amlG (G:)
    mgdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrrasa
    agvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsmrlrsveeltqfflr
    eiqygiedtgiragiikvattgkvtpfqelvlraaaraslatgvpvtthtaasqrggeqq
    aaileseglspsrvcighsdaaddlsyhtalaargyligldsiphsavglgdnasasahl
    girswqtrallikalidqgytkqilvsndwlfgissyvtnimdvmdsgnpdgmafiplrv
    ipflrekgipqetlagitvtnparflsptlras
    

    Sequence, based on observed residues (ATOM records): (download)
    >6amlG (G:)
    gdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrrasaa
    gvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsmrlrsveeltqfflre
    iqygiedtgiragiikvattgkvtpfqelvlraaaraslatgvpvtthtaasqrggeqqa
    aileseglspsrvcighsdaaddlsyhtalaargyligldsiphsavrswqtrallikal
    idqgytkqilvsndwlfgissyvtnimdvmdsgnpdgmafiplrvipflrekgipqetla
    gitvtnparflsptl