PDB entry 6akr
View 6akr on RCSB PDB site
Description: Crystal structure of the PDE4D catalytic domain in complex with osthole
Class: hydrolase
Keywords: phosphodiesterase 4d, HYDROLASE
Deposited on
2018-09-03, released
2020-02-12
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-12-02, with a file datestamp of
2020-11-27.
Experiment type: XRAY
Resolution: 2.33 Å
R-factor: N/A
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Species: Homo sapiens [TaxId:9606]
Gene: PDE4D
Database cross-references and differences (RAF-indexed):
- Chain 'B':
Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Species: Homo sapiens [TaxId:9606]
Gene: PDE4D
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6akrb_ - Chain 'C':
Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Species: Homo sapiens [TaxId:9606]
Gene: PDE4D
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Species: Homo sapiens [TaxId:9606]
Gene: PDE4D
Database cross-references and differences (RAF-indexed):
- Heterogens: A0O, ZN, HOH
PDB Chain Sequences:
- Chain 'A':
No sequence available.
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6akrB (B:)
gshmiprfgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllkt
fkipvdtlitylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaai
fasaihdvdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltk
kqrqslrkmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmv
hcadlsnptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfid
yivhplwetwadlvhpdaqdildtlednrewyqstipqspspapddpeegrqgqtekfqf
eltl
Sequence, based on observed residues (ATOM records): (download)
>6akrB (B:)
fgvkteqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdt
litylmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihd
vdhpgvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslr
kmvidivlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsn
ptkplqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplw
etwadlvhpdaqdildtlednrewyqsti
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.