PDB entry 6aah

View 6aah on RCSB PDB site
Description: Crystal structure of JAK1 in complex with peficitinib
Class: transferase/inhibitor
Keywords: protein kinase, TRANSFERASE-INHIBITOR complex
Deposited on 2018-07-18, released 2018-08-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-08-15, with a file datestamp of 2018-08-10.
Experiment type: XRAY
Resolution: 1.83 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase JAK1
    Species: Homo sapiens [TaxId:9606]
    Gene: JAK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6aaha_
  • Chain 'B':
    Compound: Tyrosine-protein kinase JAK1
    Species: Homo sapiens [TaxId:9606]
    Gene: JAK1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 9T6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6aahA (A:)
    vdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpesggnhiadlkk
    eieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknknkinlkqqlkya
    vqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdsp
    vfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrl
    vntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6aahA (A:)
    vdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkphiadlkkeieil
    rnlyhenivkykgictedggngiklimeflpsgslkeylpknknkinlkqqlkyavqick
    gmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdspvfwya
    peclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrlvntlk
    egkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk
    

  • Chain 'B':
    No sequence available.