PDB entry 5zka

View 5zka on RCSB PDB site
Description: Crystal structure of N-acetylneuraminate lyase from Fusobacterium nucleatum complexed with Pyruvate
Class: lyase
Keywords: N-acetylneuraminate lyase, Sialic acid catabolism, TIM-barrel, Schiff base, LYASE
Deposited on 2018-03-23, released 2018-12-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-12-05, with a file datestamp of 2018-11-30.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: n-acetylneuraminate lyase
    Species: Fusobacterium nucleatum subsp. nucleatum ATCC 25586 [TaxId:190304]
    Gene: nanA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RDN6 (17-End)
      • expression tag (14-16)
    Domains in SCOPe 2.07: d5zkaa1, d5zkaa2
  • Chain 'B':
    Compound: n-acetylneuraminate lyase
    Species: Fusobacterium nucleatum subsp. nucleatum ATCC 25586 [TaxId:190304]
    Gene: nanA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8RDN6 (7-295)
      • expression tag (0-6)
    Domains in SCOPe 2.07: d5zkab1, d5zkab2
  • Heterogens: EDO, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5zkaA (A:)
mhhhhhhitslykkagfmkgiysalmvpynedgsinekglreiirynidkmkvdglyvgg
stgenfmisteekkrvfeiaideakdsvnliaqvgsinlneavelgkyvtklgykclsav
tpfyykfdfseikdyyetivretgnymiiysipfltgvnmslsqfgelfenekiigvxft
agdfyllervrkafpdklifagfdemllpatvlgvdgaigstyningirakqifelakns
kidealkiqhttndliegilsnglyqtikeilklegvdagycrkpmkkisqkqiefakel
hkkflkn

    Sequence, based on observed residues (ATOM records): (download) 
    >5zkaA (A:)
agfmkgiysalmvpynedgsinekglreiirynidkmkvdglyvggstgenfmisteekk
rvfeiaideakdsvnliaqvgsinlneavelgkyvtklgykclsavtpfyykfdfseikd
yyetivretgnymiiysipfltgvnmslsqfgelfenekiigvxftagdfyllervrkaf
pdklifagfdemllpatvlgvdgaigstyningirakqifelaknskidealkiqhttnd
liegilsnglyqtikeilklegvdagycrkpmkkisqkqiefakelhkkflk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5zkaB (B:)
lykkagfmkgiysalmvpynedgsinekglreiirynidkmkvdglyvggstgenfmist
eekkrvfeiaideakdsvnliaqvgsinlneavelgkyvtklgykclsavtpfyykfdfs
eikdyyetivretgnymiiysipfltgvnmslsqfgelfenekiigvkftagdfyllerv
rkafpdklifagfdemllpatvlgvdgaigstyningirakqifelaknskidealkiqh
ttndliegilsnglyqtikeilklegvdagycrkpmkkisqkqiefakelhkkflk

    Sequence, based on observed residues (ATOM records): (download) 
    >5zkaB (B:)
lykkagfmkgiysalmvpynedgsinekglreiirynidkmkvdglyvggstgenfmist
eekkrvfeiaideakdsvnliaqvgsinlneavelgkyvtklgykclsavtpfyfdfsei
kdyyetivretgnymiiysipfltgvnmslsqfgelfenekiigvkftagdfyllervrk
afpdklifagfdemllpatvlgvdgaigstyningirakqifelaknskidealkiqhtt
ndliegilsnglyqtikeilklegvdagycrkpmkkisqkqiefakelhkkflk