PDB entry 5zjd

View 5zjd on RCSB PDB site
Description: Lactate dehydrogenase with NADH and MLA
Class: oxidoreductase
Keywords: LDHA, NADH, Oxidoreductase
Deposited on 2018-03-20, released 2019-07-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: L-lactate dehydrogenase A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHA, PIG19
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5zjda1, d5zjda2
  • Chain 'B':
    Compound: L-lactate dehydrogenase A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHA, PIG19
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5zjdb1, d5zjdb2
  • Chain 'C':
    Compound: L-lactate dehydrogenase A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHA, PIG19
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5zjdc1, d5zjdc2
  • Chain 'D':
    Compound: L-lactate dehydrogenase A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHA, PIG19
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5zjdd1, d5zjdd2
  • Chain 'E':
    Compound: L-lactate dehydrogenase A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHA, PIG19
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5zjde1, d5zjde2
  • Chain 'F':
    Compound: L-lactate dehydrogenase A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHA, PIG19
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5zjdf1, d5zjdf2
  • Chain 'G':
    Compound: L-lactate dehydrogenase A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHA, PIG19
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5zjdg1, d5zjdg2
  • Chain 'H':
    Compound: L-lactate dehydrogenase A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: LDHA, PIG19
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5zjdh1, d5zjdh2
  • Heterogens: MLI, NAI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5zjdA (A:)
hhhhhhatlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdvie
dklkgemmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvn
ifkfiipnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmg
erlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvv
esayeviklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcil
gqngisdlvkvtltseeearlkksadtlwgiqkelqf

    Sequence, based on observed residues (ATOM records): (download) 
    >5zjdA (A:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5zjdB (B:)
hhhhhhatlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdvie
dklkgemmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvn
ifkfiipnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmg
erlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvv
esayeviklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcil
gqngisdlvkvtltseeearlkksadtlwgiqkelqf

    Sequence, based on observed residues (ATOM records): (download) 
    >5zjdB (B:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5zjdC (C:)
hhhhhhatlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdvie
dklkgemmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvn
ifkfiipnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmg
erlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvv
esayeviklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcil
gqngisdlvkvtltseeearlkksadtlwgiqkelqf

    Sequence, based on observed residues (ATOM records): (download) 
    >5zjdC (C:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5zjdD (D:)
hhhhhhatlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdvie
dklkgemmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvn
ifkfiipnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmg
erlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvv
esayeviklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcil
gqngisdlvkvtltseeearlkksadtlwgiqkelqf

    Sequence, based on observed residues (ATOM records): (download) 
    >5zjdD (D:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5zjdE (E:)
hhhhhhatlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdvie
dklkgemmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvn
ifkfiipnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmg
erlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvv
esayeviklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcil
gqngisdlvkvtltseeearlkksadtlwgiqkelqf

    Sequence, based on observed residues (ATOM records): (download) 
    >5zjdE (E:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5zjdF (F:)
hhhhhhatlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdvie
dklkgemmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvn
ifkfiipnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmg
erlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvv
esayeviklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcil
gqngisdlvkvtltseeearlkksadtlwgiqkelqf

    Sequence, based on observed residues (ATOM records): (download) 
    >5zjdF (F:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5zjdG (G:)
hhhhhhatlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdvie
dklkgemmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvn
ifkfiipnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmg
erlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvv
esayeviklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcil
gqngisdlvkvtltseeearlkksadtlwgiqkelqf

    Sequence, based on observed residues (ATOM records): (download) 
    >5zjdG (G:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5zjdH (H:)
hhhhhhatlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdvie
dklkgemmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvn
ifkfiipnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmg
erlgvhplschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvv
esayeviklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcil
gqngisdlvkvtltseeearlkksadtlwgiqkelqf

    Sequence, based on observed residues (ATOM records): (download) 
    >5zjdH (H:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf