PDB entry 5z8z

View 5z8z on RCSB PDB site
Description: BRD4 Bromodomain 1 with an inhibitor
Class: transcription/inhibitor
Keywords: BRD4 Bromodomain 1, inhibitor, complex, TRANSCRIPTION-INHIBITOR complex
Deposited on 2018-02-01, released 2019-02-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-02-06, with a file datestamp of 2019-02-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60885 (2-126)
      • expression tag (0-1)
    Domains in SCOPe 2.07: d5z8za1, d5z8za2
  • Heterogens: 99R, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5z8zA (A:)
    smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
    ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
    nelptee