PDB entry 5z4o

View 5z4o on RCSB PDB site
Description: Bacterial GyrB ATPase domain in complex with a chemical fragment
Class: isomerase
Keywords: DNA Topoisomerase, Antibacterial, Drug Target, Fragment-base Lead Discovery, ISOMERASE
Deposited on 2018-01-12, released 2018-12-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-12-12, with a file datestamp of 2018-12-07.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA gyrase subunit b
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: gyrB, acrB, cou, himB, hisU, nalC, parA, pcbA, b3699, JW5625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5z4oa_
  • Chain 'B':
    Compound: DNA gyrase subunit b
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: gyrB, acrB, cou, himB, hisU, nalC, parA, pcbA, b3699, JW5625
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5z4ob_
  • Heterogens: HX8, PO4, AX7, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5z4oA (A:)
gldavrkrpgmyigdtddgtglhhmvfevvdnaidealaghckeiivtihadnsvsvqdd
grgiptgihpeegvsaaevimtvlhaggkfddnsykvsgglhgvgvsvvnalsqklelvi
qregkihrqiyehgvpqaplavtgetektgtmvrfwpsletftnvtefeyeilakrlrel
sflnsgvsirlrdkrdgkedhfhyegg

    Sequence, based on observed residues (ATOM records): (download) 
    >5z4oA (A:)
ldavrkrpgmyigdtddgtglhhmvfevvdnaidealaghckeiivtihadnsvsvqddg
rgiptgihpeegvsaaevimtvlvgvsvvnalsqklelviqregkihrqiyehgvpqapl
avtgetektgtmvrfwpsletftnvtefeyeilakrlrelsflnsgvsirlrdkrdgked
hfhy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5z4oB (B:)
gldavrkrpgmyigdtddgtglhhmvfevvdnaidealaghckeiivtihadnsvsvqdd
grgiptgihpeegvsaaevimtvlhaggkfddnsykvsgglhgvgvsvvnalsqklelvi
qregkihrqiyehgvpqaplavtgetektgtmvrfwpsletftnvtefeyeilakrlrel
sflnsgvsirlrdkrdgkedhfhyegg

    Sequence, based on observed residues (ATOM records): (download) 
    >5z4oB (B:)
ldavrkrpgmyigdtddgtglhhmvfevvdnaidealaghckeiivtihadnsvsvqddg
rgiptgihpeegvsaaevimtvlgvgvsvvnalsqklelviqregkihrqiyehgvpqap
lavtgetektgtmvrfwpsletftnvtefeyeilakrlrelsflnsgvsirlrdkrdgke
dhfhyeg