PDB entry 5ywh

View 5ywh on RCSB PDB site
Description: Crystal structure of Arabidopsis thaliana HPPD complexed with Y13508
Class: oxidoreductase
Keywords: 4-hydroxyphenylpyruvate dioxygenase, Type 1 Tyrosinemia, drug discovery, OXIDOREDUCTASE
Deposited on 2017-11-29, released 2019-01-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-16, with a file datestamp of 2019-01-11.
Experiment type: XRAY
Resolution: 2.72 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-hydroxyphenylpyruvate dioxygenase
    Species: Arabidopsis thaliana [TaxId:3702]
    Gene: HPD, PDS1, At1g06570, F12K11.9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ywha1, d5ywha2
  • Chain 'B':
    Compound: 4-hydroxyphenylpyruvate dioxygenase
    Species: Arabidopsis thaliana [TaxId:3702]
    Gene: HPD, PDS1, At1g06570, F12K11.9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ywhb1, d5ywhb2
  • Heterogens: FE, 92U, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5ywhA (A:)
    mghqnaavsenqnhddgaasspgfklvgfskfvrknpksdkfkvkrfhhiefwcgdatnv
    arrfswglgmrfsaksdlstgnmvhasylltsgdlrflftapyspslsageikptttasi
    psfdhgscrsffsshglgvravaievedaesafsisvangaipssppivlneavtiaevk
    lygdvvlryvsykaedtekseflpgfervedassfpldygirrldhavgnvpelgpalty
    vagftgfhqfaeftaddvgtaesglnsavlasndemvllpinepvhgtkrksqiqtyleh
    negaglqhlalmsedifrtlremrkrssiggfdfmpsppptyyqnlkkrvgdvlsddqik
    eceelgilvdrddqgtllqiftkplgdrptifieiiqrvgcmmkdeegkayqsggcggfg
    kgnfselfksieeyektleakqlvg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5ywhA (A:)
    fskfvrknpksdkfkvkrfhhiefwcgdatnvarrfswglgmrfsaksdlstgnmvhasy
    lltsgdlrflftapyspslsttasipsfdhgscrsffsshglgvravaievedaesafsi
    svangaipssppivlneavtiaevklygdvvlryvsykaflpgfervedassfpldygir
    rldhavgnvpelgpaltyvagftgfhqfaefsglnsavlasndemvllpinepvhgksqi
    qtylehnegaglqhlalmsedifrtlremrkrssiggfdfmpsppptyyqnlkkrvgdvl
    sddqikeceelgilvdrddqgtllqiftkplgdrptifieiiqrvgcmmqsggcggfgkg
    nfselfksieey
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5ywhB (B:)
    mghqnaavsenqnhddgaasspgfklvgfskfvrknpksdkfkvkrfhhiefwcgdatnv
    arrfswglgmrfsaksdlstgnmvhasylltsgdlrflftapyspslsageikptttasi
    psfdhgscrsffsshglgvravaievedaesafsisvangaipssppivlneavtiaevk
    lygdvvlryvsykaedtekseflpgfervedassfpldygirrldhavgnvpelgpalty
    vagftgfhqfaeftaddvgtaesglnsavlasndemvllpinepvhgtkrksqiqtyleh
    negaglqhlalmsedifrtlremrkrssiggfdfmpsppptyyqnlkkrvgdvlsddqik
    eceelgilvdrddqgtllqiftkplgdrptifieiiqrvgcmmkdeegkayqsggcggfg
    kgnfselfksieeyektleakqlvg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5ywhB (B:)
    fskfvrknpksdkfkvkrfhhiefwcgdatnvarrfswglgmrfsaksdlstgnmvhasy
    lltsgdlrflftapyspslttasipsfdhgscrsffsshglgvravaievedaesafsis
    vangaipssppivlneavtiaevklygdvvlryvsykaflpgfervedassfpldygirr
    ldhavgnvpelgpaltyvagftgfhqfaefsglnsavlasndemvllpinepvksqiqty
    lehnegaglqhlalmsedifrtlremrkrssiggfdfmpsppptyyqnlkkrvgdvlsdd
    qikeceelgilvdrddqgtllqiftkplgdrptifieiiqrvgcmmyqsggcggfgkgnf
    selfksieey