PDB entry 5ylt

View 5ylt on RCSB PDB site
Description: Crystal structure of SET7/9 in complex with a cyproheptadine derivative
Class: transferase/transferase inhibitor
Keywords: Set domain, methyltransferase, inhibitor, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2017-10-19, released 2018-06-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-06-20, with a file datestamp of 2018-06-15.
Experiment type: XRAY
Resolution: 1.69 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase SETD7
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD7, KIAA1717, KMT7, SET7, SET9
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ylta1, d5ylta2
  • Heterogens: SFG, C7N, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5yltA (A:)
gssgssgkdnirhgvcwiyypdggslvgevnedgemtgekiayvypdertalygkfidge
miegklatlmsteegrphfelmpgnsvyhfdkstsscistnallpdpyeservyvaesli
ssageglfskvavgpntvmsfyngvrithqevdsrdwalngntlsldeetvidvpepynh
vskycaslghkanhsftpnciydmfvhprfgpikcirtlraveadeeltvaygydhsppg
ksgpeapewyqvelkafqatqqk

    Sequence, based on observed residues (ATOM records): (download) 
    >5yltA (A:)
rhgvcwiyypdggslvgevnedgemtgekiayvypdertalygkfidgemiegklatlms
teegrphfelmpgnsvyhfdkstsscistnallpdpyeservyvaeslissageglfskv
avgpntvmsfyngvrithqevdsrdwalngntlsldeetvidvpepynhvskycaslghk
anhsftpnciydmfvhprfgpikcirtlraveadeeltvaygydhsppgksapewyqvel
kafqatq