PDB entry 5y9j

View 5y9j on RCSB PDB site
Description: BAFF in complex with belimumab
Class: protein binding
Keywords: BAFF, belimumab, antibody, lupus, PROTEIN BINDING
Deposited on 2017-08-25, released 2018-02-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-04, with a file datestamp of 2019-08-30.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tumor necrosis factor ligand superfamily member 13b
    Species: Homo sapiens [TaxId:9606]
    Gene: TNFSF13B, BAFF, BLYS, TALL1, TNFSF20, ZTNF4, UNQ401/PRO738
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5y9ja_
  • Chain 'H':
    Compound: belimumab heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5Y9J
    Domains in SCOPe 2.08: d5y9jh1, d5y9jh2
  • Chain 'L':
    Compound: belibumab light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5Y9J
    Domains in SCOPe 2.08: d5y9jl1, d5y9jl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5y9jA (A:)
avqgpeetvtqdclqliadsetptiqkgsytfvpwllsfkrgsaleekenkilvketgyf
fiygqvlytdktyamghliqrkkvhvfgdelslvtlfrciqnmpetlpnnscysagiakl
eegdelqlaiprenaqisldgdvtffgalkll

    Sequence, based on observed residues (ATOM records): (download) 
    >5y9jA (A:)
vtqdclqliadsetptiqkgsytfvpwllsfkrgsaleekenkilvketgyffiygqvly
tdktyamghliqrkkvhvfgdelslvtlfrciqnmpetlpnnscysagiakleegdelql
aiprenaqisldgdvtffgalkll

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5y9jH (H:)
qvqlqqsgaevkkpgssvrvsckasggtfnnnainwvrqapgqglewmggiipmfgtaky
sqnfqgrvaitadestgtasmelsslrsedtavyycarsrdlllfphhalspwgrgtmvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5y9jH (H:)
vqlqqsgaevkkpgssvrvsckasggtfnnnainwvrqapgqglewmggiipmfgtakys
qnfqgrvaitadestgtasmelsslrsedtavyycarsrdlllfphhalspwgrgtmvtv
ssastkgpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >5y9jL (L:)
sseltqdpavsvalgqtvrvtcqgdslrsyyaswyqqkpgqapvlviygknnrpsgipdr
fsgsssgntasltitgaqaedeadyycssrdssgnhwvfgggteltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5y9jL (L:)
seltqdpavsvalgqtvrvtcqgdslrsyyaswyqqkpgqapvlviygknnrpsgipdrf
sgsssgntasltitgaqaedeadyycssrdssgnhwvfgggteltvlgqpkaapsvtlfp
psseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassyls
ltpeqwkshrsyscqvthegstvektvapt