PDB entry 5xyj

View 5xyj on RCSB PDB site
Description: Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
Class: transferase
Keywords: Acetoacetyl-CoA thiolase, Claisen condension, The mevalonate pathway, TRANSFERASE
Deposited on 2017-07-08, released 2018-07-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-07-11, with a file datestamp of 2018-07-06.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetyl-CoA acetyltransferase
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: ERG10, YPL028W, LPB3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41338 (Start-407)
      • engineered mutation (100)
    Domains in SCOPe 2.08: d5xyja1, d5xyja2
  • Chain 'B':
    Compound: Acetyl-CoA acetyltransferase
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: ERG10, YPL028W, LPB3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41338 (Start-407)
      • engineered mutation (100)
    Domains in SCOPe 2.08: d5xyjb1, d5xyjb2
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5xyjA (A:)
mghhhhhhgsmsqnvyivstartpigsfqgslssktavelgavalkgalakvpeldaskd
fdeiifgnvlsanlgqaparqvalaaglsnhivastvnkvaasamkaiilgaqsikcgna
dvvvaggcesmtnapyympaaragakfgqtvlvdgverdglndaydglamgvhaekcard
wditreqqdnfaiesyqksqksqkegkfdneivpvtikgfrgkpdtqvtkdeeparlhve
klrsartvfqkengtvtaanaspindgaaavilvsekvlkeknlkplaiikgwgeaahqp
adftwapslavpkalkhagiedinsvdyfefneafsvvglvntkilkldpskvnvyggav
alghplgcsgarvvvtllsilqqeggkigvaaicnggggassivieki

    Sequence, based on observed residues (ATOM records): (download) 
    >5xyjA (A:)
qnvyivstartpigsfqgslssktavelgavalkgalakvpeldaskdfdeiifgnvlsa
nlgqaparqvalaaglsnhivastvnkvaasamkaiilgaqsikcgnadvvvaggcesmt
napyympaaragakfgqtvlvdgverdglndaydglamgvhaekcardwditreqqdnfa
iesyqksqksqkegkfdneivpvtikgfrgkpdtqvtkdeeparlhveklrsartvfqke
ngtvtaanaspindgaaavilvsekvlkeknlkplaiikgwgeaahqpadftwapslavp
kalkhagiedinsvdyfefneafsvvglvntkilkldpskvnvyggavalghplgcsgar
vvvtllsilqqeggkigvaaicnggggassivieki

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5xyjB (B:)
mghhhhhhgsmsqnvyivstartpigsfqgslssktavelgavalkgalakvpeldaskd
fdeiifgnvlsanlgqaparqvalaaglsnhivastvnkvaasamkaiilgaqsikcgna
dvvvaggcesmtnapyympaaragakfgqtvlvdgverdglndaydglamgvhaekcard
wditreqqdnfaiesyqksqksqkegkfdneivpvtikgfrgkpdtqvtkdeeparlhve
klrsartvfqkengtvtaanaspindgaaavilvsekvlkeknlkplaiikgwgeaahqp
adftwapslavpkalkhagiedinsvdyfefneafsvvglvntkilkldpskvnvyggav
alghplgcsgarvvvtllsilqqeggkigvaaicnggggassivieki

    Sequence, based on observed residues (ATOM records): (download) 
    >5xyjB (B:)
qnvyivstartpigsfqgslssktavelgavalkgalakvpeldaskdfdeiifgnvlsa
nlgqaparqvalaaglsnhivastvnkvaasamkaiilgaqsikcgnadvvvaggcesmt
napyympaaragakfgqtvlvdgverdglndaydglamgvhaekcardwditreqqdnfa
iesyqksqksqkegkfdneivpvtikgfrgkpdtqvtkdeeparlhveklrsartvfqke
ngtvtaanaspindgaaavilvsekvlkeknlkplaiikgwgeaahqpadftwapslavp
kalkhagiedinsvdyfefneafsvvglvntkilkldpskvnvyggavalghplgcsgar
vvvtllsilqqeggkigvaaicnggggassivieki