PDB entry 5xmp

View 5xmp on RCSB PDB site
Description: Plasmodium vivax SHMT(C346A) bound with PLP-glycine and MF057
Class: transferase/transferase inhibitor
Keywords: alpha and beta protein, methyltransferase activity, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2017-05-16, released 2017-11-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-29, with a file datestamp of 2017-11-24.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine hydroxymethyltransferase
    Species: Plasmodium vivax [TaxId:5855]
    Gene: PVC01_140059500, PVP01_1453700, PVT01_140059000
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1G4H5I1 (0-441)
      • engineered mutation (363)
    Domains in SCOPe 2.07: d5xmpa_
  • Chain 'B':
    Compound: serine hydroxymethyltransferase
    Species: Plasmodium vivax [TaxId:5855]
    Gene: PVC01_140059500, PVP01_1453700, PVT01_140059000
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1G4H5I1 (0-441)
      • engineered mutation (363)
    Domains in SCOPe 2.07: d5xmpb_
  • Chain 'C':
    Compound: serine hydroxymethyltransferase
    Species: Plasmodium vivax [TaxId:5855]
    Gene: PVC01_140059500, PVP01_1453700, PVT01_140059000
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1G4H5I1 (0-441)
      • engineered mutation (363)
    Domains in SCOPe 2.07: d5xmpc_
  • Heterogens: PLG, 8A3, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5xmpA (A:)
mfnnepleqidkelhdiladeekrqretinliasenltngavreclgnrvsnkysegypk
kryyggndfidkieelcqkraleafnvsdeewgvnvqplsgsaanvqalyalvgvkgkim
gmhlcsgghlthgffdekkkvsitsdmfesklykcnsqgyvdldavremalsfkpkviic
gytsyprdidyqqfrqicdevnaylfadishissfvacnilnnpflhadvvtttthkilr
gprsaliffnkkrnpgieqkinsavfpsfqggphnnkiaavacqlkevhspafkeytqqv
llnskalakaliskqidlvtngtdnhlivvdlrkfsitgsklqetcnainvslnkntips
dvdavspsgvrigtpamttrgakekdmefiadvlaraikitvdlqeqygkklvdfkkglp
gnaqlqqlkqevvtwagalpfp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5xmpB (B:)
mfnnepleqidkelhdiladeekrqretinliasenltngavreclgnrvsnkysegypk
kryyggndfidkieelcqkraleafnvsdeewgvnvqplsgsaanvqalyalvgvkgkim
gmhlcsgghlthgffdekkkvsitsdmfesklykcnsqgyvdldavremalsfkpkviic
gytsyprdidyqqfrqicdevnaylfadishissfvacnilnnpflhadvvtttthkilr
gprsaliffnkkrnpgieqkinsavfpsfqggphnnkiaavacqlkevhspafkeytqqv
llnskalakaliskqidlvtngtdnhlivvdlrkfsitgsklqetcnainvslnkntips
dvdavspsgvrigtpamttrgakekdmefiadvlaraikitvdlqeqygkklvdfkkglp
gnaqlqqlkqevvtwagalpfp

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5xmpC (C:)
mfnnepleqidkelhdiladeekrqretinliasenltngavreclgnrvsnkysegypk
kryyggndfidkieelcqkraleafnvsdeewgvnvqplsgsaanvqalyalvgvkgkim
gmhlcsgghlthgffdekkkvsitsdmfesklykcnsqgyvdldavremalsfkpkviic
gytsyprdidyqqfrqicdevnaylfadishissfvacnilnnpflhadvvtttthkilr
gprsaliffnkkrnpgieqkinsavfpsfqggphnnkiaavacqlkevhspafkeytqqv
llnskalakaliskqidlvtngtdnhlivvdlrkfsitgsklqetcnainvslnkntips
dvdavspsgvrigtpamttrgakekdmefiadvlaraikitvdlqeqygkklvdfkkglp
gnaqlqqlkqevvtwagalpfp