PDB entry 5xk9

View 5xk9 on RCSB PDB site
Description: Crystal structure of Isosesquilavandulyl Diphosphate Synthase from Streptomyces sp. strain CNH-189 in complex with GSPP and DMAPP
Class: transferase
Keywords: prenyltransferase, antibiotic biosynthesis, TRANSFERASE
Deposited on 2017-05-05, released 2018-01-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Undecaprenyl diphosphate synthase
    Species: Streptomyces sp. CNH189 [TaxId:1136432]
    Gene: mcl22
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5xk9a_
  • Chain 'B':
    Compound: Undecaprenyl diphosphate synthase
    Species: Streptomyces sp. CNH189 [TaxId:1136432]
    Gene: mcl22
    Database cross-references and differences (RAF-indexed):
    • Uniprot M4T4U9 (15-End)
      • expression tag (14)
    Domains in SCOPe 2.08: d5xk9b1, d5xk9b2
  • Chain 'C':
    Compound: Undecaprenyl diphosphate synthase
    Species: Streptomyces sp. CNH189 [TaxId:1136432]
    Gene: mcl22
    Database cross-references and differences (RAF-indexed):
    • Uniprot M4T4U9 (15-231)
      • expression tag (14)
    Domains in SCOPe 2.08: d5xk9c1, d5xk9c2
  • Chain 'D':
    Compound: Undecaprenyl diphosphate synthase
    Species: Streptomyces sp. CNH189 [TaxId:1136432]
    Gene: mcl22
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5xk9d_
  • Chain 'E':
    Compound: Undecaprenyl diphosphate synthase
    Species: Streptomyces sp. CNH189 [TaxId:1136432]
    Gene: mcl22
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5xk9e_
  • Chain 'F':
    Compound: Undecaprenyl diphosphate synthase
    Species: Streptomyces sp. CNH189 [TaxId:1136432]
    Gene: mcl22
    Database cross-references and differences (RAF-indexed):
    • Uniprot M4T4U9 (15-End)
      • expression tag (14)
    Domains in SCOPe 2.08: d5xk9f1, d5xk9f2
  • Chain 'G':
    Compound: Undecaprenyl diphosphate synthase
    Species: Streptomyces sp. CNH189 [TaxId:1136432]
    Gene: mcl22
    Database cross-references and differences (RAF-indexed):
    • Uniprot M4T4U9 (15-End)
      • expression tag (14)
    Domains in SCOPe 2.08: d5xk9g1, d5xk9g2
  • Chain 'H':
    Compound: Undecaprenyl diphosphate synthase
    Species: Streptomyces sp. CNH189 [TaxId:1136432]
    Gene: mcl22
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5xk9h_
  • Heterogens: MG, GST, DMA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5xk9A (A:)
    mahhhhhhvddddkmmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegf
    ttfyvtvssvanysrseeqvttamnaftevvrrchdtlnfnysgtlevvperwlteleal
    raksdsqsdftlhfimgmslahevigifnkfngkipalteellaanayvpepvdflirpg
    ghvrmssfyplmspfaemyfcptllndmtradfdvaledlrerdrryglypv
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xk9A (A:)
    mtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegfttfyvtvssvanysr
    seeqvttamnaftevvrrchdtlnfnysgtlevvperwltelealraksdsqsdftlhfi
    mgmslahevigifnkfngkipalteellaanayvpepvdflirpgghvrmssfyplmspf
    aemyfcptllndmtradfdvaledlrerdrrygl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5xk9B (B:)
    mahhhhhhvddddkmmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegf
    ttfyvtvssvanysrseeqvttamnaftevvrrchdtlnfnysgtlevvperwlteleal
    raksdsqsdftlhfimgmslahevigifnkfngkipalteellaanayvpepvdflirpg
    ghvrmssfyplmspfaemyfcptllndmtradfdvaledlrerdrryglypv
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xk9B (B:)
    mmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegfttfyvtvssvanys
    rseeqvttamnaftevvrrchdtlnfnysgtlevvperwltelealraksdsqsdftlhf
    imgmslahevigifnkfngkipalteellaanayvpepvdflirpgghvrmssfyplmsp
    faemyfcptllndmtradfdvaledlrer
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5xk9C (C:)
    mahhhhhhvddddkmmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegf
    ttfyvtvssvanysrseeqvttamnaftevvrrchdtlnfnysgtlevvperwlteleal
    raksdsqsdftlhfimgmslahevigifnkfngkipalteellaanayvpepvdflirpg
    ghvrmssfyplmspfaemyfcptllndmtradfdvaledlrerdrryglypv
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xk9C (C:)
    mmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegfttfyvtvssvanys
    rseeqvttamnaftevvrrchdtlnfnysgtlevvperwltelealraksdsqsdftlhf
    imgmslahevigifnkfngkipalteellaanayvpepvdflirpgghvrmssfyplmsp
    faemyfcptllndmtradfdvaledlrerdrryglypv
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5xk9D (D:)
    mahhhhhhvddddkmmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegf
    ttfyvtvssvanysrseeqvttamnaftevvrrchdtlnfnysgtlevvperwlteleal
    raksdsqsdftlhfimgmslahevigifnkfngkipalteellaanayvpepvdflirpg
    ghvrmssfyplmspfaemyfcptllndmtradfdvaledlrerdrryglypv
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xk9D (D:)
    mtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegfttfyvtvssvanysr
    seeqvttamnaftevvrrchdtlnfnysgtlevvperwltelealraksdsqsdftlhfi
    mgmslahevigifnkfngkipalteellaanayvpepvdflirpgghvrmssfyplmspf
    aemyfcptllndmtradfdvaledlrerd
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >5xk9E (E:)
    mahhhhhhvddddkmmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegf
    ttfyvtvssvanysrseeqvttamnaftevvrrchdtlnfnysgtlevvperwlteleal
    raksdsqsdftlhfimgmslahevigifnkfngkipalteellaanayvpepvdflirpg
    ghvrmssfyplmspfaemyfcptllndmtradfdvaledlrerdrryglypv
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xk9E (E:)
    mtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegfttfyvtvssvanysr
    seeqvttamnaftevvrrchdtlnfnysgtlevvperwltelealraksdsqsdftlhfi
    mgmslahevigifnkfngkipalteellaanayvpepvdflirpgghvrmssfyplmspf
    aemyfcptllndmtradfdvaledlrerdrrygl
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >5xk9F (F:)
    mahhhhhhvddddkmmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegf
    ttfyvtvssvanysrseeqvttamnaftevvrrchdtlnfnysgtlevvperwlteleal
    raksdsqsdftlhfimgmslahevigifnkfngkipalteellaanayvpepvdflirpg
    ghvrmssfyplmspfaemyfcptllndmtradfdvaledlrerdrryglypv
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xk9F (F:)
    mmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegfttfyvtvssvanys
    rseeqvttamnaftevvrrchdtlnfnysgtlevvperwltelealraksdsqsdftlhf
    imgmslahevigifnkfngkipalteellaanayvpepvdflirpgghvrmssfyplmsp
    faemyfcptllndmtradfdvaledlrer
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >5xk9G (G:)
    mahhhhhhvddddkmmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegf
    ttfyvtvssvanysrseeqvttamnaftevvrrchdtlnfnysgtlevvperwlteleal
    raksdsqsdftlhfimgmslahevigifnkfngkipalteellaanayvpepvdflirpg
    ghvrmssfyplmspfaemyfcptllndmtradfdvaledlrerdrryglypv
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xk9G (G:)
    mmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegfttfyvtvssvanys
    rseeqvttamnaftevvrrchdtlnfnysgtlevvperwltelealraksdsqsdftlhf
    imgmslahevigifnkfngkipalteellaanayvpepvdflirpgghvrmssfyplmsp
    faemyfcptllndmtradfdvaledlrerdrryglyp
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >5xk9H (H:)
    mahhhhhhvddddkmmtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegf
    ttfyvtvssvanysrseeqvttamnaftevvrrchdtlnfnysgtlevvperwlteleal
    raksdsqsdftlhfimgmslahevigifnkfngkipalteellaanayvpepvdflirpg
    ghvrmssfyplmspfaemyfcptllndmtradfdvaledlrerdrryglypv
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xk9H (H:)
    mtnlmllpdgmrrwsqkqgislddsyaamtdklveftgwareegfttfyvtvssvanysr
    seeqvttamnaftevvrrchdtlnfnysgtlevvperwltelealraksdsqsdftlhfi
    mgmslahevigifnkfngkipalteellaanayvpepvdflirpgghvrmssfyplmspf
    aemyfcptllndmtradfdvaledlrer