PDB entry 5xjl

View 5xjl on RCSB PDB site
Description: crystal structure of the gemin2-binding domain of smn, gemin2 in complex with smd1/d2/f/e/g from human
Deposited on 2017-05-02, released 2018-05-02
The last revision was dated 2018-05-02, with a file datestamp of 2018-04-27.
No data on structure quality are available

Chains and heterogens:

  • Chain '2':
    Compound: Gem-associated protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: GEMIN2, SIP1
    Database cross-references and differences (RAF-indexed):
  • Chain 'A':
    Compound: Small nuclear ribonucleoprotein Sm D1
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Small nuclear ribonucleoprotein Sm D2
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD2, SNRPD1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Small nuclear ribonucleoprotein E
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPE
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Small nuclear ribonucleoprotein F
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPF, PBSCF
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Small nuclear ribonucleoprotein G
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPG, PBSCG
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: Survival motor neuron protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SMN1, SMN, SMNT, SMN2, SMNC
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.04, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain '2':
    Sequence, based on SEQRES records:
    >5xjl2 (2:)
mrraelaglktmawvpaesaveelmprllpvepcdltegfdpsvpprtpqeylrrvqiea
aqcpdvvvaqidpkklkrkqsvnislsgcqpapegysptlqwqqqqvaqfstvrqnvnkh
rshwksqqldsnvtmpksedeegwkkfclgeklcadgavgpatnespgidyvqigfppll
sivsrmnqatvtsvleylsnwfgerdftpelgrwlyallaclekpllpeahslirqlarr
csevrllvdskddervpalnlliclvsryfdqrdladeps

    Sequence, based on observed residues (ATOM records):
    >5xjl2 (2:)
eelmprllpvtpqeylrrvqieaaqcpdvvvaqidpkqsvnislsgcqpapegysptlqw
qqqqvaqfstvrqnvnkhrshwmpksedeegwkkfclgeigfppllsivsrmnqatvtsv
leylsnwfgerdftpelgrwlyallaclekpllpeahslirqlarrcsevrllvdskdde
rvpalnlliclvsryfdqrdlade

  • Chain 'A':
    Sequence, based on SEQRES records:
    >5xjlA (A:)
mklvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsi
rgnniryfilpdslpldtllvdvepkvkskkreavagrgrgrgrgrgrgrgrgrggprr

    Sequence, based on observed residues (ATOM records):
    >5xjlA (A:)
mklvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsi
rgnniryfilpdslpldtllv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >5xjlB (B:)
msllnkpksemtpeelqkreeeefntgplsvltqsvknntqvlincrnnkkllgrvkafd
rhcnmvlenvkemwtevpksgkgkkkskpvnkdryiskmflrgdsvivvlrnpliagk

    Sequence, based on observed residues (ATOM records):
    >5xjlB (B:)
eefntgplsvltqsvknntqvlincrnnkkllgrvkafdrhcnmvlenvkemwtevpvnk
dryiskmflrgdsvivvlrnpliag

  • Chain 'E':
    Sequence, based on SEQRES records:
    >5xjlE (E:)
mayrgqgqkvqkvmvqpinlifrylqnrsriqvwlyeqvnmriegciigfdeymnlvldd
aeeihsktksrkqlgrimlkgdnitllqsvsn

    Sequence, based on observed residues (ATOM records):
    >5xjlE (E:)
mvqpinlifrylqnrsriqvwlyeqvnmriegciigfdeymnlvlddaeeihsktksrkq
lgrimlkgdnitllqsv

  • Chain 'F':
    Sequence, based on SEQRES records:
    >5xjlF (F:)
mslplnpkpflngltgkpvmvklkwgmeykgylvsvdgymnmqlanteeyidgalsghlg
evlircnnvlyirgveeeeedgemre

    Sequence, based on observed residues (ATOM records):
    >5xjlF (F:)
lplnpkpflngltgkpvmvklkwgmeykgylvsvdgymnmqlanteeyidgalsghlgev
lircnnvlyirgve

  • Chain 'G':
    Sequence, based on SEQRES records:
    >5xjlG (G:)
mskahppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmv
virgnsiimlealerv

    Sequence, based on observed residues (ATOM records):
    >5xjlG (G:)
elkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgnnigmvvirgnsiim
lea

  • Chain 'M':
    Sequence, based on SEQRES records:
    >5xjlM (M:)
gqsddsdiwddtalikaydkavasfkhalkngdicet

    Sequence, based on observed residues (ATOM records):
    >5xjlM (M:)
ddtalikaydkavasfk