PDB entry 5xis

View 5xis on RCSB PDB site
Description: Crystal structure of RNF168 UDM1 in complex with Lys63-linked diubiquitin, form I
Class: transferase/ribosomal protein
Keywords: ubiquitin, TRANSFERASE-RIBOSOMAL PROTEIN complex
Deposited on 2017-04-27, released 2018-03-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-03-28, with a file datestamp of 2018-03-23.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase RNF168
    Species: Homo sapiens [TaxId:9606]
    Gene: RNF168
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Ubiquitin-40S ribosomal protein S27a
    Species: Mus musculus [TaxId:10090]
    Gene: Rps27a, Uba80, Ubcep1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5xisb_
  • Chain 'C':
    Compound: Ubiquitin-40S ribosomal protein S27a
    Species: Mus musculus [TaxId:10090]
    Gene: Rps27a, Uba80, Ubcep1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62983 (0-75)
      • engineered mutation (62)
    Domains in SCOPe 2.07: d5xisc_
  • Chain 'D':
    Compound: E3 ubiquitin-protein ligase RNF168
    Species: Homo sapiens [TaxId:9606]
    Gene: RNF168
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8IYW5 (5-83)
      • expression tag (2-4)
  • Chain 'E':
    Compound: Ubiquitin-40S ribosomal protein S27a
    Species: Mus musculus [TaxId:10090]
    Gene: Rps27a, Uba80, Ubcep1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5xise_
  • Chain 'F':
    Compound: Ubiquitin-40S ribosomal protein S27a
    Species: Mus musculus [TaxId:10090]
    Gene: Rps27a, Uba80, Ubcep1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62983 (0-75)
      • engineered mutation (62)
    Domains in SCOPe 2.07: d5xisf_
  • Heterogens: XYZ, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5xisB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrggd
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xisB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlr
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5xisC (C:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqrestlhlvlrlrgg
    

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >5xisE (E:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrggd
    

    Sequence, based on observed residues (ATOM records): (download)
    >5xisE (E:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrl
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5xisF (F:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqrestlhlvlrlrgg