PDB entry 5xhk

View 5xhk on RCSB PDB site
Description: Crystal structure of the BRD2-BD2 in complex with phenanthridinone
Class: transcription
Keywords: bromodomain, BET family, BRD2, Phenanthridinone, TRANSCRIPTION
Deposited on 2017-04-21, released 2017-09-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-06, with a file datestamp of 2017-09-01.
Experiment type: XRAY
Resolution: 1.28 Å
R-factor: N/A
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD2, KIAA9001, RING3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25440 (7-114)
      • expression tag (0-6)
    Domains in SCOPe 2.07: d5xhka1, d5xhka2
  • Heterogens: GOL, 2ME, LDR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5xhkA (A:)
    aahgsnpeqlkhcngilkellskkhaayawpfykpvdasalglhdyhdiikhpmdlstvk
    rkmenrdyrdaqefaadvrlmfsncykynppdhdvvamarklqdvfefryakmpd