PDB entry 5xbh

View 5xbh on RCSB PDB site
Description: Crystal structure of R145E mutant of thymidylate kinase (aq_969) from Aquifex Aeolicus VF5
Class: transferase
Keywords: Kinase, Complex, Nucleotide Binding, TRANSFERASE
Deposited on 2017-03-17, released 2017-06-28
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-06-28, with a file datestamp of 2017-06-23.
Experiment type: XRAY
Resolution: 2.23 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thymidylate kinase
    Species: Aquifex aeolicus (strain VF5) [TaxId:224324]
    Gene: tmk, aq_969
    Database cross-references and differences (RAF-indexed):
    • Uniprot O67099 (0-End)
      • engineered mutation (144)
    Domains in SCOPe 2.06: d5xbha_
  • Chain 'B':
    Compound: thymidylate kinase
    Species: Aquifex aeolicus (strain VF5) [TaxId:224324]
    Gene: tmk, aq_969
    Database cross-references and differences (RAF-indexed):
    • Uniprot O67099 (0-End)
      • engineered mutation (144)
    Domains in SCOPe 2.06: d5xbhb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5xbhA (A:)
mliafegidgsgkttqakklyeylkqkgyfvslyrepggtkvgevlreillteelderte
lllfeasrsklieekiipdlkrdkvvildrfvlstiayqgygkgldvefiknlnefatrg
vkpditllldipvdialrrlkeknefenkeflekvrkgflelakeeenvvvidasgeeee
vfkeilralsgvlrv

    Sequence, based on observed residues (ATOM records): (download) 
    >5xbhA (A:)
mliafegidgsgkttqakklyeylkqkgyfvslyrepggtkvgevlreillteelderte
lllfeasrsklieekiipdlkrdkvvildrfvlstiayqgygkgldvefiknlnefatrg
vkpditllldipvdialrrlkeknefenkeflekvrkgflelakeeenvvvidasgeeee
vfkeilralsgvlr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5xbhB (B:)
mliafegidgsgkttqakklyeylkqkgyfvslyrepggtkvgevlreillteelderte
lllfeasrsklieekiipdlkrdkvvildrfvlstiayqgygkgldvefiknlnefatrg
vkpditllldipvdialrrlkeknefenkeflekvrkgflelakeeenvvvidasgeeee
vfkeilralsgvlrv

    Sequence, based on observed residues (ATOM records): (download) 
    >5xbhB (B:)
mliafegidgsgkttqakklyeylkqkgyfvslyrepggtkvgevlreillteelderte
lllfeasrsklieekiipdlkrdkvvildrfvlstiayqgygkgldvefiknlnefatrg
vkpditllldipvdialrrlkeknefenkeflekvrkgflelakeeenvvvidasgeeee
vfkeilralsgvlr