PDB entry 5x3v

View 5x3v on RCSB PDB site
Description: Structure of human SHMT2 protein mutant
Class: transferase
Keywords: Serine hydroxymethyltransferase, TRANSFERASE
Deposited on 2017-02-09, released 2018-02-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-02-14, with a file datestamp of 2018-02-09.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine hydroxymethyltransferase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: SHMT2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P34897 (Start-482)
      • engineered mutation (73)
    Domains in SCOPe 2.07: d5x3va_
  • Chain 'B':
    Compound: Serine hydroxymethyltransferase, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: SHMT2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P34897 (Start-482)
      • engineered mutation (73)
    Domains in SCOPe 2.07: d5x3vb_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5x3vA (A:)
mairaqhsnaaqtqtgeanrgwtgqeslsdsdpemwellqrekdrqcrgleliasenfcs
raalealgsclnnrysegypgkryyggaevvdeiellcqrraleafdldpaqwgvnvqpy
sgspanlavytallqphdrimgldlpdgghlthgymsdvkrisatsiffesmpyklnpkt
glidynqlaltarlfrprliiagtsayarlidyarmrevcdevkahlladmahisglvaa
kvipspfkhadivtttthktlrgarsglifyrkgvkavdpktgreipytfedrinfavfp
slqggphnhaiaavavalkqactpmfreyslqvlknaramadallergyslvsggtdnhl
vlvdlrpkgldgaraervlelvsitankntcpgdrsaitpgglrlgapaltsrqfreddf
rrvvdfidegvniglevksktaklqdfksfllkdsetsqrlanlrqrveqfarafpmpgf
dehklaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5x3vA (A:)
wtgqeslsdsdpemwellqrekdrqcrgleliasenfcsraalealgsclnnrysegypg
kryyggaevvdeiellcqrraleafdldpaqwgvnvqpysgspanlavytallqphdrim
gldlpdgghltisatsiffesmpyklnpktglidynqlaltarlfrprliiagtsayarl
idyarmrevcdevkahlladmahisglvaakvipspfkhadivtttthktlrgarsglif
yrkgvkeipytfedrinfavfpslqggphnhaiaavavalkqactpmfreyslqvlknar
amadallergyslvsggtdnhlvlvdlrpkgldgaraervlelvsitankntcpgdrsai
tpgglrlgapaltsrqfreddfrrvvdfidegvniglevksktaklqdfksfllkdsets
qrlanlrqrveqfarafpmpgfdeh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5x3vB (B:)
mairaqhsnaaqtqtgeanrgwtgqeslsdsdpemwellqrekdrqcrgleliasenfcs
raalealgsclnnrysegypgkryyggaevvdeiellcqrraleafdldpaqwgvnvqpy
sgspanlavytallqphdrimgldlpdgghlthgymsdvkrisatsiffesmpyklnpkt
glidynqlaltarlfrprliiagtsayarlidyarmrevcdevkahlladmahisglvaa
kvipspfkhadivtttthktlrgarsglifyrkgvkavdpktgreipytfedrinfavfp
slqggphnhaiaavavalkqactpmfreyslqvlknaramadallergyslvsggtdnhl
vlvdlrpkgldgaraervlelvsitankntcpgdrsaitpgglrlgapaltsrqfreddf
rrvvdfidegvniglevksktaklqdfksfllkdsetsqrlanlrqrveqfarafpmpgf
dehklaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5x3vB (B:)
wtgqeslsdsdpemwellqrekdrqcrgleliasenfcsraalealgsclnnrysegypg
kryyggaevvdeiellcqrraleafdldpaqwgvnvqpysgspanlavytallqphdrim
gldlpdgghlrisatsiffesmpyklnpktglidynqlaltarlfrprliiagtsayarl
idyarmrevcdevkahlladmahisglvaakvipspfkhadivtttthktlrgarsglif
yrkgvipytfedrinfavfpslqggphnhaiaavavalkqactpmfreyslqvlknaram
adallergyslvsggtdnhlvlvdlrpkgldgaraervlelvsitankntcpgdsaitpg
glrlgapaltsrqfreddfrrvvdfidegvniglevksktaklqdfksfllkdsetsqrl
anlrqrveqfarafpmpgfdeh