PDB entry 5wt9

View 5wt9 on RCSB PDB site
Description: Complex structure of PD-1 and nivolumab-Fab
Class: immune system
Keywords: PD-1, Nivolumab, IMMUNE SYSTEM
Deposited on 2016-12-10, released 2017-02-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-12-13, with a file datestamp of 2017-12-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'G':
    Compound: Programmed cell death protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Pdcd1, Pd1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5wt9g_
  • Chain 'H':
    Compound: Heavy Chain of Nivolumab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WT9 (0-End)
  • Chain 'L':
    Compound: Light Chain of Nivolumab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WT9 (0-End)
    Domains in SCOPe 2.07: d5wt9l1, d5wt9l2
  • Heterogens: NAG, FUC, HOH

PDB Chain Sequences:

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5wt9G (G:)
mqipqapwpvvwavlqlgwrpgwfldspdrpwnpptfspallvvtegdnatftcsfsnts
esfvlnwyrmspsnqtdklaafpedrsqpgqdcrfrvtqlpngrdfhmsvvrarrndsgt
ylcgaislapkaqikeslraelrvterraevptahpspsprpagqfqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wt9G (G:)
ldspdrpwnpptfspallvvtegdnatftcsfsntsesfvlnwyrmspsnqtdklaafpe
rfrvtqlpngrdfhmsvvrarrndsgtylcgaislapkaqikeslrael

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >5wt9L (L:)
stgeivltqspatlslspgeratlscrasqsvssylawyqqkpgqaprlliydasnratg
iparfsgsgsgtdftltisslepedfavyycqqssnwprtfgqgtkveikrtvaapsvfi
fppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslss
tltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5wt9L (L:)
stgeivltqspatlslspgeratlscrasqsvssylawyqqkpgqaprlliydasnratg
iparfsgsgsgtdftltisslepedfavyycqqssnwprtfgqgtkveikrtvaapsvfi
fppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslss
tltlskadyekhkvyacevthqglsspvtksfnrge