PDB entry 5wt5

View 5wt5 on RCSB PDB site
Description: L-homocysteine-bound NifS from Helicobacter pylori
Class: transferase
Keywords: Iron-sulfur cluster biogenesis, cysteine desulfurase, TRANSFERASE
Deposited on 2016-12-09, released 2017-12-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-12-13, with a file datestamp of 2017-12-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cysteine desulfurase IscS
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: iscS, HP_0220
    Database cross-references and differences (RAF-indexed):
    • Uniprot O25008
      • engineered mutation (1)
      • engineered mutation (137)
    Domains in SCOPe 2.08: d5wt5a_
  • Chain 'B':
    Compound: Cysteine desulfurase IscS
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: iscS, HP_0220
    Database cross-references and differences (RAF-indexed):
    • Uniprot O25008
      • engineered mutation (1)
      • engineered mutation (137)
    Domains in SCOPe 2.08: d5wt5b_
  • Chain 'C':
    Compound: Cysteine desulfurase IscS
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: iscS, HP_0220
    Database cross-references and differences (RAF-indexed):
    • Uniprot O25008
      • engineered mutation (1)
      • engineered mutation (137)
    Domains in SCOPe 2.08: d5wt5c_
  • Chain 'D':
    Compound: Cysteine desulfurase IscS
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: iscS, HP_0220
    Database cross-references and differences (RAF-indexed):
    • Uniprot O25008
      • engineered mutation (1)
      • engineered mutation (137)
    Domains in SCOPe 2.08: d5wt5d_
  • Heterogens: IPA, HCS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5wt5A (A:)
mvqriyldnnattridpkvkeimdpflrdhygnpsslhqfgtethpaiaealdklykgin
ardiddviitscatesnnwvlkgvyfdeclkkgknhivttvaehpavrstcnfleslgve
vtylpinehgsitaeqvreaitektalvsvmwannetglifpieeigaickekgvlfhtd
avqaigkipvdvlkanadflsfsahkfhgpkgigglyirsgvgltplfhggehmngrrsg
tlnvpyivgmgeamklavehldyekevvgklrdkleeallkipdvmvvgdrihrvpnttl
vsvrgiegeamlwdlnrsniaastgsacasedleanpvmvaigaskelahtairlslsrf
nteaeidktievfsqaavrlrnisssyvdlvprgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wt5A (A:)
vqriyldnnattridpkvkeimdpflrdhygnpsslhqfgtethpaiaealdklykgina
rdiddviitscatesnnwvlkgvyfdeclkkgknhivttvaehpavrstcnfleslgvev
tylpinehgsitaeqvreaitektalvsvmwannetglifpieeigaickekgvlfhtda
vqaigkipvdvlkanadflsfsahkfhgpkgigglyirsgvgltplfhggehmngrrsgt
lnvpyivgmgeamklavehldyekevvgklrdkleeallkipdvmvvgdrihrvpnttlv
svrgiegeamlwdlnrsniaastgsachtairlslsrfnteaeidktievfsqaavrlrn
iss

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5wt5B (B:)
mvqriyldnnattridpkvkeimdpflrdhygnpsslhqfgtethpaiaealdklykgin
ardiddviitscatesnnwvlkgvyfdeclkkgknhivttvaehpavrstcnfleslgve
vtylpinehgsitaeqvreaitektalvsvmwannetglifpieeigaickekgvlfhtd
avqaigkipvdvlkanadflsfsahkfhgpkgigglyirsgvgltplfhggehmngrrsg
tlnvpyivgmgeamklavehldyekevvgklrdkleeallkipdvmvvgdrihrvpnttl
vsvrgiegeamlwdlnrsniaastgsacasedleanpvmvaigaskelahtairlslsrf
nteaeidktievfsqaavrlrnisssyvdlvprgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wt5B (B:)
vqriyldnnattridpkvkeimdpflrdhygnpsslhqfgtethpaiaealdklykgina
rdiddviitscatesnnwvlkgvyfdeclkkgknhivttvaehpavrstcnfleslgvev
tylpinehgsitaeqvreaitektalvsvmwannetglifpieeigaickekgvlfhtda
vqaigkipvdvlkanadflsfsahkfhgpkgigglyirsgvgltplfhggehmngrrsgt
lnvpyivgmgeamklavehldyekevvgklrdkleeallkipdvmvvgdrihrvpnttlv
svrgiegeamlwdlnrsniaastgsacahtairlslsrfnteaeidktievfsqaavrlr
nis

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5wt5C (C:)
mvqriyldnnattridpkvkeimdpflrdhygnpsslhqfgtethpaiaealdklykgin
ardiddviitscatesnnwvlkgvyfdeclkkgknhivttvaehpavrstcnfleslgve
vtylpinehgsitaeqvreaitektalvsvmwannetglifpieeigaickekgvlfhtd
avqaigkipvdvlkanadflsfsahkfhgpkgigglyirsgvgltplfhggehmngrrsg
tlnvpyivgmgeamklavehldyekevvgklrdkleeallkipdvmvvgdrihrvpnttl
vsvrgiegeamlwdlnrsniaastgsacasedleanpvmvaigaskelahtairlslsrf
nteaeidktievfsqaavrlrnisssyvdlvprgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wt5C (C:)
vqriyldnnattridpkvkeimdpflrdhygnpsslhqfgtethpaiaealdklykgina
rdiddviitscatesnnwvlkgvyfdeclkkgknhivttvaehpavrstcnfleslgvev
tylpinehgsitaeqvreaitektalvsvmwannetglifpieeigaickekgvlfhtda
vqaigkipvdvlkanadflsfsahkfhgpkgigglyirsgvgltplfhggehmngrrsgt
lnvpyivgmgeamklavehldyekevvgklrdkleeallkipdvmvvgdrihrvpnttlv
svrgiegeamlwdlnrsniaastgsachtairlslsrfnteaeidktievfsqaavrlrn
isss

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5wt5D (D:)
mvqriyldnnattridpkvkeimdpflrdhygnpsslhqfgtethpaiaealdklykgin
ardiddviitscatesnnwvlkgvyfdeclkkgknhivttvaehpavrstcnfleslgve
vtylpinehgsitaeqvreaitektalvsvmwannetglifpieeigaickekgvlfhtd
avqaigkipvdvlkanadflsfsahkfhgpkgigglyirsgvgltplfhggehmngrrsg
tlnvpyivgmgeamklavehldyekevvgklrdkleeallkipdvmvvgdrihrvpnttl
vsvrgiegeamlwdlnrsniaastgsacasedleanpvmvaigaskelahtairlslsrf
nteaeidktievfsqaavrlrnisssyvdlvprgshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wt5D (D:)
vqriyldnnattridpkvkeimdpflrdhygnpsslhqfgtethpaiaealdklykgina
rdiddviitscatesnnwvlkgvyfdeclkkgknhivttvaehpavrstcnfleslgvev
tylpinehgsitaeqvreaitektalvsvmwannetglifpieeigaickekgvlfhtda
vqaigkipvdvlkanadflsfsahkfhgpkgigglyirsgvgltplfhggehmngrrsgt
lnvpyivgmgeamklavehldyekevvgklrdkleeallkipdvmvvgdrihrvpnttlv
svrgiegeamlwdlnrsniaastgsacahtairlslsrfnteaeidktievfsqaavrlr
nisss