PDB entry 5wnk

View 5wnk on RCSB PDB site
Description: Crystal structure of murine receptor-interacting protein 4 (Ripk4) D143N bound to TG100-115
Class: transferase/transferase inhibitor
Keywords: Kinase, Inhibitor, Complex, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2017-08-01, released 2018-05-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-05-16, with a file datestamp of 2018-05-11.
Experiment type: XRAY
Resolution: 3.11 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor-interacting serine/threonine-protein kinase 4
    Species: Mus musculus [TaxId:10090]
    Gene: Ripk4, Ankrd3, Pkk
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9ERK0
      • engineered mutation (142)
    Domains in SCOPe 2.08: d5wnka_
  • Heterogens: CL, B6J, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5wnkA (A:)
    megegrgrwalgllrtfdagefagwekvgsggfgqvykvrhvhwktwlaikcspslhvdd
    rermelleeakkmemakfryilpvygicqepvglvmeymetgslekllaseplpwdlrfr
    ivhetavgmnflhcmsppllhlnlkpanilldahyhvkisdfglakcngmshshdlsmdg
    lfgtiaylpperireksrlfdtkhdvysfaiviwgvltqkkpfadeknilhimmkvvkgh
    rpelppicrprpracasliglmqrcwhadpqvrptfqeitsetedlcekpdeevkdlahe
    pgeksslesksearpessrlkrasappfdndcslsellsqld
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wnkA (A:)
    algllrtfdagefagwekvgsfgqvykvrhvhwktwlaikcspslhvddrermelleeak
    kmemakfryilpvygicqepvglvmeymetgslekllaseplpwdlrfrivhetavgmnf
    lhcmsppllhlnlkpanilldahyhvkisdfglakcfgtiaylpperireksrlfdtkhd
    vysfaiviwgvltqkkpfadeknilhimmkvvkghrpelppicrprpracasliglmqrc
    whadpqvrptfqeitsetedlce