PDB entry 5wmv

View 5wmv on RCSB PDB site
Description: Structural Insights into Substrate and Inhibitor Binding Sites in Human Indoleamine 2,3-Dioxygenase 1
Class: oxidoreductase
Keywords: Dioxygenase Tryptophan Heme Inhibitor, OXIDOREDUCTASE
Deposited on 2017-07-31, released 2017-12-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Indoleamine 2,3-dioxygenase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: IDO1, IDO, INDO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wmva_
  • Chain 'B':
    Compound: Indoleamine 2,3-dioxygenase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: IDO1, IDO, INDO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wmvb_
  • Heterogens: CYN, HEM, TRP, ZCW, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5wmvA (A:)
mskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhl
tdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcv
lanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqm
qerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvye
gfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsl
esnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktsed
pskleakgtggtdlmnflktvrstteksllkegkgelnsklegkpipnpllgldstrtgh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wmvA (A:)
keyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhltd
hksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvla
nwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmqe
rdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyegf
wedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsles
npsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkleakgtggt
dlmnflktvrstteksllkeg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5wmvB (B:)
mskeyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhl
tdhksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcv
lanwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqm
qerdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvye
gfwedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsl
esnpsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpkenktsed
pskleakgtggtdlmnflktvrstteksllkegkgelnsklegkpipnpllgldstrtgh
hhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wmvB (B:)
keyhideevgfalpnpqenlpdfyndwmfiakhlpdliesgqlrerveklnmlsidhltd
hksqrlarlvlgcitmayvwgkghgdvrkvlprniavpycqlskklelppilvyadcvla
nwkkkdpnkpltyenmdvlfsfrdgdcskgfflvsllveiaaasaikviptvfkamqmqe
rdtllkalleiasclekalqvfhqihdhvnpkaffsvlriylsgwkgnpqlsdglvyegf
wedpkefaggsagqssvfqcfdvllgiqqtaggghaaqflqdmrrymppahrnflcsles
npsvrefvlskgdaglreaydacvkalvslrsyhlqivtkyilipasqqpleakgtggtd
lmnflktvrstteksllkeg