PDB entry 5wlr

View 5wlr on RCSB PDB site
Description: Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide
Class: lyase/inhibitor
Keywords: carbonic anhydrase, beta adrenergic receptor, sulfonamide, aryloxy-2-hydroxypropylammine, LYASE, LYASE-INHIBITOR complex
Deposited on 2017-07-27, released 2018-08-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-08-01, with a file datestamp of 2018-07-27.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic Anhydrase IX-mimic
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00918 (0-256)
      • conflict (61)
      • conflict (63)
      • conflict (65)
      • conflict (87)
      • conflict (126)
      • conflict (165)
      • conflict (199)
    Domains in SCOPe 2.07: d5wlra_
  • Heterogens: 86B, ZN, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5wlrA (A:)
    hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
    hsfqvtfddsqdkavlkggpldgtyrllqfhfhwgsldgqgsehtvdkkkyaaelhlvhw
    ntkygdvgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktegksadftnfdprgl
    lpesldywtypgslttpplaecvtwivlkepisvsseqvlkfrklnfngegepeelmvdn
    wrpaqplknrqikasfk