PDB entry 5wkl

View 5wkl on RCSB PDB site
Description: 1.85 A resolution structure of MERS 3CL protease in complex with piperidine-based peptidomimetic inhibitor 17
Class: hydrolase/hydrolase inhibitor
Keywords: PROTEASE, protease Inhhibitors, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2017-07-25, released 2018-04-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-04-04, with a file datestamp of 2018-03-29.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Orf1a protein
    Species: Middle East respiratory syndrome-related coronavirus [TaxId:1335626]
    Gene: ORF1a
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5wkla1, d5wkla2
  • Heterogens: AVY, B3J, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5wklA (A:)
mhhhhhhsglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpn
ydallismtnhsfsvqkhigapanlrvvghamqgtllkltvdvanpstpaytfttvkpga
afsvlacyngrptgtftvvmrpnytikgsflcgscgsvgytkegsvinfcymhqmelang
thtgsafdgtmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsf
newalanqftefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftp
edvnmqimgvvmq

    Sequence, based on observed residues (ATOM records): (download) 
    >5wklA (A:)
hhsglvkmshpsgdveacmvqvtcgsmtlnglwldntvwcprhvmcpadqlsdpnydall
ismtnhsfsvqkhianlrvvghamqgtllkltvdvanpstpaytfttvkpgaafsvlacy
ngrptgtftvvmrpnytikgsflcgscgsvgytkegsvinfcymhqmelangthtgsafd
gtmygafmdkqvhqvqltdkycsvnvvawlyaailngcawfvkpnrtsvvsfnewalanq
ftefvgtqsvdmlavktgvaieqllyaiqqlytgfqgkqilgstmledeftpedvnmqim
gvv