PDB entry 5wki

View 5wki on RCSB PDB site
Description: Crystal structure of PG90 TCR-CD1b-PG complex
Class: immune system
Keywords: antigen presenting molecule, PG, phospholipid, MHC, CD1b, PG90, T-cell Receptor, TCR, autoreactive, IMMUNE SYSTEM
Deposited on 2017-07-25, released 2017-11-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein cd1b
    Species: Homo sapiens [TaxId:9606]
    Gene: CD1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wkia1, d5wkia2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wkib_
  • Chain 'D':
    Compound: T-cell receptor alpha variable 26-1,TRA@ protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TRA@
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A087WT03 (Start-89)
      • conflict (7)
      • linker (90-109)
    • Uniprot Q6P4G7 (110-End)
      • conflict (157)
    Domains in SCOPe 2.08: d5wkid1, d5wkid2
  • Chain 'E':
    Compound: PG90 TCR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5WKI (Start-248)
    Domains in SCOPe 2.08: d5wkie1, d5wkie2
  • Heterogens: CUY, NAG, EDO, NA, D3D, ACT, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5wkiA (A:)
hafqgptsfhviqtssftnstwaqtqgsgwlddlqihgwdsdsgtaiflkpwskgnfsdk
evaeleeifrvyifgfarevqdfagdfqmkypfeiqgiagcelhsggaivsflrgalggl
dflsvknascvpspeggsraqkfcaliiqyqgimetvrillyetcpryllgvlnagkadl
qrqvkpeawlssgpspgpgrlqlvchvsgfypkpvwvmwmrgeqeqqgtqlgdilpnanw
twylratldvadgeaaglscrvkhsslegqdiilywrgsglndifeaqkiewhehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wkiA (A:)
gptsfhviqtssftnstwaqtqgsgwlddlqihgwdsdsgtaiflkpwskgnfsdkevae
leeifrvyifgfarevqdfagdfqmkypfeiqgiagcelhsaivsflrgalggldflsvk
nascvpspeggsraqkfcaliiqyqgimetvrillyetcpryllgvlnagkadlqrqvkp
eawlssgpsgrlqlvchvsgfypkpvwvmwmrgeqeqqgtqlgdilpnanwtwylratld
vadgeaaglscrvkhsslegqdiilyw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5wkiB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

    Sequence, based on observed residues (ATOM records): (download) 
    >5wkiB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5wkiD (D:)
dakttqppsmdcaegraanlpcnhstisgneyvywyrqihsqgpqyiihglknnetnema
sliitedrksstlilphatlrdtavyycivrvayrqkvtfgtgtklqvipniqnpdpavy
qlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksd
facanafnnsiipedtffpspess

    Sequence, based on observed residues (ATOM records): (download) 
    >5wkiD (D:)
kttqppsmdcaegraanlpcnhstisgneyvywyrqihsqgpqyiihglknnetnemasl
iitedrksstlilphatlrdtavyycivrvayrqkvtfgtgtklqvipniqnpdpavyql
rdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsnksdfa
canafnnsiipedtffps

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5wkiE (E:)
gagvsqsprykvakrgqdvalrcdpisghvslfwyqqalgqgpefltyfqneaqldksgl
psdrffaerpegsvstlkiqrtqqedsavylcasslaraqgasntgelffgegsrltvle
dlknvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpq
plkeqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqiv
saeawgrad

    Sequence, based on observed residues (ATOM records): (download) 
    >5wkiE (E:)
agvsqsprykvakrgqdvalrcdpisghvslfwyqqalgqgpefltyfqneaqldksglp
sdrffaerpegsvstlkiqrtqqedsavylcasslaraqgasntgelffgegsrltvled
lknvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqp
lkeqpalndsryalssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivs
aeawgrad