PDB entry 5wgi

View 5wgi on RCSB PDB site
Description: Ultrahigh resolution crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with TSA
Class: hydrolase/hydrolase inhibitor
Keywords: histone deacetylase, hydrolase inhibitor, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2017-07-14, released 2017-12-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-12-20, with a file datestamp of 2017-12-15.
Experiment type: XRAY
Resolution: 1.05 Å
R-factor: N/A
AEROSPACI score: 0.77 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hdac6 protein
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed):
    • Uniprot A7YT55 (5-363)
      • expression tag (1-4)
    Domains in SCOPe 2.07: d5wgia1, d5wgia2
  • Heterogens: ZN, TSN, K, CL, EDO, GOL, PEG, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5wgiA (A:)
snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
sslr

    Sequence, based on observed residues (ATOM records): (download) 
    >5wgiA (A:)
naggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlat
eeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqa
iltgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhh
gngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgd
peymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaag
rvliileggynltsisesmsmctsmllgdsppsltplktsatvsinnvlrahapfwsslr