PDB entry 5wfq

View 5wfq on RCSB PDB site
Description: Ligand-bound Ras:SOS:Ras complex
Class: signaling protein
Keywords: Ras, SOS, ONCOPROTEIN, Protein-protein interaction, MAPK, SIGNALING PROTEIN
Deposited on 2017-07-12, released 2018-05-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-05-23, with a file datestamp of 2018-05-18.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'N':
    Compound: Son of sevenless homolog 1
    Species: Homo sapiens [TaxId:9606]
    Gene: SOS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wfqn_
  • Chain 'Q':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wfqq_
  • Chain 'R':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01112 (1-166)
      • expression tag (0)
    Domains in SCOPe 2.08: d5wfqr1, d5wfqr2
  • Heterogens: MG, GNP, 5UV, HOH

PDB Chain Sequences:

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >5wfqN (N:)
gqmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfv
rtflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqp
vqlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiar
dngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpsel
vgsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqe
lnnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinp
pcvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrve
sdikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsn
pr

    Sequence, based on observed residues (ATOM records): (download) 
    >5wfqN (N:)
qmrlpsadvyrfaepdseeniifeenmqgipiikagtviklierltyhmyadpnfvrtfl
ttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvqlr
vlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkianitfq
sspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselvgsvwtkedke
inspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqelnnfngvlevv
samnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcvpffgiylt
nilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenln
pmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsnpr

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >5wfqQ (Q:)
gmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

    Sequence, based on observed residues (ATOM records): (download) 
    >5wfqQ (Q:)
mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5wfqR (R:)
gmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh