PDB entry 5wfp

View 5wfp on RCSB PDB site
Description: Ligand-bound Ras:SOS:Ras complex
Class: signaling protein
Keywords: Ras, SOS, ONCOPROTEIN, Protein-protein complex, MAPK, SIGNALING PROTEIN
Deposited on 2017-07-12, released 2018-05-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-05-23, with a file datestamp of 2018-05-18.
Experiment type: XRAY
Resolution: 2.08 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'N':
    Compound: Son of sevenless homolog 1
    Species: Homo sapiens [TaxId:9606]
    Gene: SOS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5wfpn_
  • Chain 'Q':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5wfpq_
  • Chain 'R':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01112 (1-166)
      • expression tag (0)
    Domains in SCOPe 2.07: d5wfpr1, d5wfpr2
  • Heterogens: MG, GNP, 5UX, HOH

PDB Chain Sequences:

  • Chain 'N':
    Sequence, based on SEQRES records: (download)
    >5wfpN (N:)
    gqmrlpsadvyrfaepdseeniifeenmqpkagipiikagtviklierltyhmyadpnfv
    rtflttyrsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqp
    vqlrvlnvcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkiar
    dngpghnitfqsspptvewhisrpghietfdlltlhpieiarqltllesdlyravqpsel
    vgsvwtkedkeinspnllkmirhttnltlwfekcivetenleervavvsriieilqvfqe
    lnnfngvlevvsamnsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinp
    pcvpffgiyltnilkteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrve
    sdikrffenlnpmgnsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsn
    pr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wfpN (N:)
    qmrlpsadvyrfaepdseeniifeegipiikagtviklierltyhmyadpnfvrtfltty
    rsfckpqellsliierfeipepepteadriaiengdqplsaelkrfrkeyiqpvqlrvln
    vcrhwvehhfydferdayllqrmeefigtvrgkamkkwvesitkiiqrkkianitfqssp
    ptvewhisrpghietfdlltlhpieiarqltllesdlyravqpselvgsvwtkedkeins
    pnllkmirhttnltlwfekcivetenleervavvsriieilqvfqelnnfngvlevvsam
    nsspvyrldhtfeqipsrqkkileeahelsedhykkylaklrsinppcvpffgiyltnil
    kteegnpevlkrhgkelinfskrrkvaeitgeiqqyqnqpyclrvesdikrffenlnpmg
    nsmekeftdylfnksleieprnpkplprfpkkysyplkspgvrpsnpr
    

  • Chain 'Q':
    Sequence, based on SEQRES records: (download)
    >5wfpQ (Q:)
    gmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
    gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
    laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wfpQ (Q:)
    mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
    qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
    aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh
    

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5wfpR (R:)
    gmteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildta
    gqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcd
    laartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh