PDB entry 5wcp

View 5wcp on RCSB PDB site
Description: Phosphotriesterase variant S7
Class: hydrolase
Keywords: phosphotriesterase, organophosphate hydrolase, epistasis, directed evolution, laboratory evolution, HYDROLASE
Deposited on 2017-07-01, released 2019-01-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-01-23, with a file datestamp of 2019-01-18.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphotriesterase variant PTE-R1
    Species: Brevundimonas diminuta [TaxId:293]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A060GZX0
      • conflict (183)
      • conflict (200-201)
      • conflict (221)
      • conflict (260)
      • conflict (273)
      • conflict (287)
    Domains in SCOPe 2.07: d5wcpa_
  • Chain 'G':
    Compound: Phosphotriesterase variant PTE-R1
    Species: Brevundimonas diminuta [TaxId:293]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A060GZX0
      • conflict (183)
      • conflict (200-201)
      • conflict (221)
      • conflict (260)
      • conflict (273)
      • conflict (287)
    Domains in SCOPe 2.07: d5wcpg_
  • Heterogens: ZN, CAC, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5wcpA (A:)
    mgdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrrara
    agvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsmrlrsveeltqfflr
    eiqygiedtgiragiikvattgkvtpfqelvlraaaraslatgvpvtthtaasqrggeqq
    aaileseglspsrvcighsdaaddlsyltalaargyligldsiphsaiglgdnasasahl
    girswqtrallikalidqgytkqilvsndwlfgissyvtnimdvmdsgnpdgmafiplrv
    ipflrekgipqetlagitvtnparflsptlras
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wcpA (A:)
    gdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrraraa
    gvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsmrlrsveeltqfflre
    iqygiedtgiragiikvattgkvtpfqelvlraaaraslatgvpvtthtaasqrggeqqa
    aileseglspsrvcighsdaaddlsyltalaargyligldsiphsairswqtrallikal
    idqgytkqilvsndwlfgissyvtnimdvmdsgnpdgmafiplrvipflrekgipqetla
    gitvtnparflsptlr
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >5wcpG (G:)
    mgdrintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrrara
    agvrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsmrlrsveeltqfflr
    eiqygiedtgiragiikvattgkvtpfqelvlraaaraslatgvpvtthtaasqrggeqq
    aaileseglspsrvcighsdaaddlsyltalaargyligldsiphsaiglgdnasasahl
    girswqtrallikalidqgytkqilvsndwlfgissyvtnimdvmdsgnpdgmafiplrv
    ipflrekgipqetlagitvtnparflsptlras
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wcpG (G:)
    drintvrgpitiseagftlthehicgssagflrawpeffgsrkalaekavrglrraraag
    vrtivdvstfdlgrdvsllaevsraadvhivaatglwldpplsmrlrsveeltqfflrei
    qygiedtgiragiikvattgkvtpfqelvlraaaraslatgvpvtthtaasqrggeqqaa
    ileseglspsrvcighsdaaddlsyltalaargyligldsiphsaswqtrallikalidq
    gytkqilvsndwlfgissyvtnimdvmdsgnpdgmafiplrvipflrekgipqetlagit
    vtnparflsptl