PDB entry 5wbh

View 5wbh on RCSB PDB site
Description: Structure of the FRB domain of mTOR bound to a substrate recruitment peptide of S6K1
Class: transferase
Keywords: transferase
Deposited on 2017-06-29, released 2017-12-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-04-18, with a file datestamp of 2018-04-13.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase mTOR
    Species: Homo sapiens [TaxId:9606]
    Gene: MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wbha_
  • Chain 'B':
    Compound: Serine/threonine-protein kinase mTOR
    Species: Homo sapiens [TaxId:9606]
    Gene: MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wbhb_
  • Chain 'C':
    Compound: Serine/threonine-protein kinase mTOR
    Species: Homo sapiens [TaxId:9606]
    Gene: MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wbhc_
  • Chain 'D':
    Compound: Serine/threonine-protein kinase mTOR
    Species: Homo sapiens [TaxId:9606]
    Gene: MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5wbhd_
  • Chain 'E':
    Compound: Serine/threonine-protein kinase mTOR
    Species: Homo sapiens [TaxId:9606]
    Gene: MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42345 (Start-98)
      • expression tag (99)
    Domains in SCOPe 2.08: d5wbhe1, d5wbhe2
  • Chain 'W':
    Compound: Ribosomal protein S6 kinase beta-1
    Species: Homo sapiens [TaxId:9606]
    Gene: RPS6KB1, STK14A
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5wbhA (A:)
    gsrvailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqayg
    rdlmeaqewcrkymksgnvkdltqawdlyyhvfrriskqsgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wbhA (A:)
    lwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrdlmea
    qewcrkymksgnvkdltqawdlyyhvfrrisk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5wbhB (B:)
    gsrvailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqayg
    rdlmeaqewcrkymksgnvkdltqawdlyyhvfrriskqsgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wbhB (B:)
    lwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrdlmea
    qewcrkymksgnvkdltqawdlyyhvfrrisk
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5wbhC (C:)
    gsrvailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqayg
    rdlmeaqewcrkymksgnvkdltqawdlyyhvfrriskqsgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wbhC (C:)
    rvailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrd
    lmeaqewcrkymksgnvkdltqawdlyyhvfrrisk
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5wbhD (D:)
    gsrvailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqayg
    rdlmeaqewcrkymksgnvkdltqawdlyyhvfrriskqsgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wbhD (D:)
    lwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrdlmea
    qewcrkymksgnvkdltqawdlyyhvfrrisk
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >5wbhE (E:)
    gsrvailwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqayg
    rdlmeaqewcrkymksgnvkdltqawdlyyhvfrriskqsgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5wbhE (E:)
    lwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrdlmea
    qewcrkymksgnvkdltqawdlyyhvfrriskqs
    

  • Chain 'W':
    No sequence available.