PDB entry 5w6v

View 5w6v on RCSB PDB site
Description: The Structure of human Argonaute-1 in complex with the hook motif of human GW182
Class: gene regulation/RNA
Keywords: RNA interference, RNA binding proteins, GW motif, GENE REGULATION-RNA complex
Deposited on 2017-06-17, released 2017-07-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.83 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein argonaute-1
    Species: Homo sapiens [TaxId:9606]
    Gene: AGO1, EIF2C1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5w6va1, d5w6va2, d5w6va3
  • Chain 'B':
    Compound: Trinucleotide repeat-containing gene 6A protein
    Species: Homo sapiens [TaxId:9606]
    Gene: TNRC6A, CAGH26, KIAA1460, TNRC6
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: RNA (5'-r(p*ap*ap*up*ap*up*up*ap*ap*ap*a)-3')
    Species: Spodoptera frugiperda [TaxId:7108]
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5w6vA (A:)
gameagpsgaaagaylpplqqvfqaprrpgigtvgkpikllanyfevdipkidvyhyevd
ikpdkcprrvnrevveymvqhfkpqifgdrkpvydgkkniytvtalpignervdfevtip
gegkdrifkvsikwlaivswrmlhealvsgqipvplesvqaldvamrhlasmrytpvgrs
ffsppegyyhplgggrevwfgfhqsvrpamwkmmlnidvsatafykaqpviefmcevldi
rnideqpkpltdsqrvrftkeikglkvevthcgqmkrkyrvcnvtrrpashqtfplqles
gqtvectvaqyfkqkynlqlkyphlpclqvgqeqkhtylplevcnivagqrcikkltdnq
tstmikatarsapdrqeeisrlmknasynldpyiqefgikvkddmtevtgrvlpapilqy
ggrnraiatpnqgvwdmrgkqfyngieikvwaiacfapqkqcreevlknftdqlrkiskd
agmpiqgqpcfckyaqgadsvepmfrhlkntysglqliivilpgktpvyaevkrvgdtll
gmatqcvqvknvvktspqtlsnlclkinvklgginnilvphqrsavfqqpviflgadvth
ppagdgkkpsitavvgsmdahpsrycatvrvqrprqeiiedlsymvrelliqfykstrfk
ptriifyrdgvpegqlpqilhyellairdaciklekdyqpgityivvqkrhhtrlfcadk
nerigksgnipagttvdtnithpfefdfylcshagiqgtsrpshyyvlwddnrftadelq
iltyqlchtyvrctrsvsipapayyarlvafraryhlvdkehdsgegshisgqsngrdpq
alakavqvhqdtlrtmyfa

    Sequence, based on observed residues (ATOM records): (download) 
    >5w6vA (A:)
fqaprrpgigtvgkpikllanyfevdipkidvyhyevdikpdkcprrvnrevveymvqhf
kpqifgdrkpvydgkkniytvtalpignervdfevtipgkdrifkvsikwlaivswrmlh
ealvsgqipvplesvqaldvamrhlasmrytpvgrsffsppegyyhplgggrevwfgfhq
svrpamwkmmlnidvsatafykaqpviefmcevldirnqpkpltdsqrvrftkeikglkv
evthckrkyrvcnvtrrpashqtfpectvaqyfkqkynlqlkyphlpclqvqkhtylple
vcnivagqrcikkltdnqtstmikatarsapdrqeeisrlmknasynldpyiqefgikvk
ddmtevtgrvlpapilqyggrnraiatpnqgvwdmrgkqfyngieikvwaiacfapqkqc
reevlknftdqlrkiskdagmpiqgqpcfckyaqgadsvepmfrhlkntysglqliivil
pgktpvyaevkrvgdtllgmatqcvqvknvvktspqtlsnlclkinvklgginnilvphq
rsavfqqpviflgadvthppakkpsitavvgsmdahpsrycatvrvqrprqeiiedlsym
vrelliqfykstrfkptriifyrdgvpegqlpqilhyellairdaciklekdyqpgityi
vvqkrhhtrlfcadknerigksgnipagttvdtnithpfefdfylcshagiqgtsrpshy
yvlwddnrftadelqiltyqlchtyvrctrsvsipapayyarlvafraryhlvddpqala
kavqvhqdtlrtmyfa

  • Chain 'B':
    No sequence available.

  • Chain 'R':
    No sequence available.