PDB entry 5w5k

View 5w5k on RCSB PDB site
Description: Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with KV70
Class: hydrolase
Keywords: histone deacetylase, hydrolase, tubulin deacetylase
Deposited on 2017-06-15, released 2018-06-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-06-27, with a file datestamp of 2018-06-22.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone deacetylase 6
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed):
    • Uniprot A7YT55 (5-363)
      • expression tag (2-4)
    Domains in SCOPe 2.07: d5w5ka1, d5w5ka2
  • Chain 'B':
    Compound: Histone deacetylase 6
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed):
    • Uniprot A7YT55 (5-363)
      • expression tag (2-4)
    Domains in SCOPe 2.07: d5w5kb1, d5w5kb2
  • Chain 'C':
    Compound: Histone deacetylase 6
    Species: Danio rerio [TaxId:7955]
    Gene: HDAC6
    Database cross-references and differences (RAF-indexed):
    • Uniprot A7YT55 (5-363)
      • expression tag (1-4)
    Domains in SCOPe 2.07: d5w5kc1, d5w5kc2
  • Heterogens: K70, ZN, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5w5kA (A:)
    snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
    teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
    ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
    hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
    dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
    grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
    sslr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5w5kA (A:)
    aggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlate
    eelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqai
    ltgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhg
    ngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdp
    eymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagr
    vliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwss
    lr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5w5kB (B:)
    snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
    teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
    ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
    hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
    dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
    grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
    sslr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5w5kB (B:)
    aggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlate
    eelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqai
    ltgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhhg
    ngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgdp
    eymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaagr
    vliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfwss
    lr
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5w5kC (C:)
    snaggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparla
    teeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaq
    ailtgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvh
    hgngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmg
    dpeymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaa
    grvliileggynltsisesmsmctsmllgdsppsldhltplktsatvsinnvlrahapfw
    sslr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5w5kC (C:)
    naggsspitglvydqrmmlhhnmwdshhpelpqrisrifsrheelrllsrchriparlat
    eeelalchsskhisiikssehmkprdlnrlgdeynsifisnesytcallaagscfnsaqa
    iltgqvrnavaivrppghhaekdtacgfcffntaaltaryaqsitreslrvlivdwdvhh
    gngtqhifeeddsvlyislhryedgaffpnsedanydkvglgkgrgynvnipwnggkmgd
    peymaafhhlvmpiarefapelvlvsagfdaargdplggfqvtpegyahlthqlmslaag
    rvliileggynltsisesmsmctsmllgdsppsldtplktsatvsinnvlrahapfwssl
    r