PDB entry 5w0c

View 5w0c on RCSB PDB site
Description: Cytochrome P450 (CYP) 2C9 TCA007 Inhibitor Complex
Class: OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor
Keywords: Inhibitor Complex, P450 Monooxygenase, Cytochrome P450 2C9, CYP2C9, OXIDOREDUCTASE-OXIDOREDUCTASE inhibitor complex
Deposited on 2017-05-30, released 2017-09-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 2C9
    Species: Homo sapiens [TaxId:9606]
    Gene: CYP2C9, CYP2C10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P11712 (Start-471)
      • expression tag (472)
    Domains in SCOPe 2.07: d5w0ca1, d5w0ca2
  • Heterogens: HEM, 9W6, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5w0cA (A:)
makktssgrgklppgptplpvignilqigikdisksltnlskvygpvftlyfglkpivvl
hgyeavkealidlgeefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmg
krsiedrvqeearclveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnl
meklnenikilsspwiqicnnfspiidyfpgthnkllknvafmksyilekvkehqesmdm
nnpqdfidcflmkmekekhnqpseftieslentavdlfgagtettsttlryalllllkhp
evtakvqeeiervigrnrspcmqdrshmpytdavvhevqryidllptslphavtcdikfr
nylipkgttilisltsvlhdnkefpnpemfdphhfldeggnfkkskyfmpfsagkricvg
ealagmelflfltsilqnfnlkslvdpknldttpvvngfasvppfyqlcfipihhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5w0cA (A:)
gklppgptplpvignilqigikdisksltnlskvygpvftlyfglkpivvlhgyeavkea
lidlgeefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkrsiedrvq
eearclveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlmeklnenik
ilsspwiqicnnfspiidyfpgthnkllknvafmksyilekvkehqesmdmnnpqdfidc
flmkmekekhnqpseftieslentavdlfgagtettsttlryalllllkhpevtakvqee
iervigrnrspcmqdrshmpytdavvhevqryidllptslphavtcdikfrnylipkgtt
ilisltsvlhdnkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgealagmelf
lfltsilqnfnlkslvdpknldttpvvngfasvppfyqlcfipi